Differential Diagnosis for Water Filled Cyst on Eyelid

• Single Most Likely Diagnosis
  • Nevus of Moll: A benign, congenital lesion that presents as a translucent, fluid-filled cyst on the eyelid, often appearing at birth or early childhood. It is caused by a blockage of the sweat glands.
• Other Likely Diagnoses
  • Sebaceous Cyst: While typically filled with a cheesy, semi-solid material, some sebaceous cysts can appear more fluid-filled, especially if they become inflamed or infected.
  • Epidermoid Cyst: These cysts are usually filled with a thick, cheesy material but can occasionally appear more fluid-filled, especially if they rupture or become infected.
  • Keratinous Cyst: Similar to epidermoid cysts, keratinous cysts can sometimes appear more fluid-filled, especially if they rupture.
• Do Not Miss Diagnoses
  • Basal Cell Carcinoma: Although less common, basal cell carcinoma can rarely present as a cystic lesion on the eyelid. Given its potential for malignancy, it's crucial not to miss this diagnosis.
  • Squamous Cell Carcinoma: Similar to basal cell carcinoma, squamous cell carcinoma can present in various forms, including as a cystic lesion, and requires prompt diagnosis and treatment.
• Rare Diagnoses
  • Dermoid Cyst: While more commonly found on the scalp or face, dermoid cysts can occasionally occur on the eyelid and may appear as a fluid-filled cyst.
  • Cystic Hygroma: Typically found in the neck, cystic hygromas are rare, benign lesions that can occasionally occur in other areas, including the eyelid, presenting as a fluid-filled cyst.