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Last updated: September 21, 2025View editorial policy

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Differential Diagnosis for Bleeding with Sex

  • Single most likely diagnosis
    • Cervicitis: This condition, which is an inflammation of the cervix, can cause bleeding after sexual intercourse. It's often due to a sexually transmitted infection (STI) and is a common cause of postcoital bleeding.
  • Other Likely diagnoses
    • Vaginal Dryness: Insufficient lubrication during sex can lead to vaginal tears or irritation, resulting in bleeding. This is common in postmenopausal women or those with hormonal imbalances.
    • Endometrial Polyps: These are growths in the lining of the uterus and can cause irregular menstrual bleeding, including bleeding after sex.
    • Uterine Fibroids: Noncancerous growths of the uterus that can cause heavy or irregular menstrual bleeding and bleeding after intercourse.
  • Do Not Miss (ddxs that may not be likely, but would be deadly if missed.)
    • Cervical Cancer: Although less common, cervical cancer can cause bleeding after sex. It's crucial to rule out this diagnosis with appropriate screening and testing.
    • Endometrial Cancer: Cancer of the uterus lining can also present with postcoital bleeding, among other symptoms.
    • Pelvic Inflammatory Disease (PID): An infection of the female reproductive organs that can cause bleeding, pain, and other severe complications if not treated promptly.
  • Rare diagnoses
    • Vaginal Cancer: A rare type of cancer that can cause bleeding, including after sexual intercourse.
    • Trauma: Physical trauma to the genital area, which could be accidental or non-accidental, and results in bleeding.
    • Blood Clotting Disorders: Certain conditions that affect blood clotting can lead to easy bruising or bleeding, including after sex. However, these would typically present with a broader range of symptoms.

Professional Medical Disclaimer

This information is intended for healthcare professionals. Any medical decision-making should rely on clinical judgment and independently verified information. The content provided herein does not replace professional discretion and should be considered supplementary to established clinical guidelines. Healthcare providers should verify all information against primary literature and current practice standards before application in patient care. Dr.Oracle assumes no liability for clinical decisions based on this content.

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