Prerenal Acute Kidney Injury (AKI) with volume depletion or decreased renal perfusion: This is the most likely diagnosis because even with good urine output, the kidneys may not be receiving enough blood flow to function properly, leading to a rise in creatinine levels. This can occur due to various reasons such as dehydration, heart failure, or liver disease.

Nephrotoxicity from medications: Certain medications like NSAIDs, aminoglycosides, and contrast agents can cause direct damage to the kidneys, leading to an increase in creatinine levels despite adequate urine output.
Postrenal AKI due to obstruction: Although less common with good urine output, partial obstruction or obstruction in a single kidney can cause a rise in creatinine levels.
Intrinsic renal disease: Conditions like acute tubular necrosis (ATN), glomerulonephritis, or vasculitis can cause an increase in creatinine levels. These conditions may present with good urine output initially.

Rhabdomyolysis: This condition, characterized by muscle breakdown, can lead to a significant increase in creatinine levels due to the release of muscle creatinine into the bloodstream. It's crucial to diagnose early as it can lead to severe kidney damage if not treated promptly.
Sepsis: Sepsis can cause AKI through various mechanisms, including hypoperfusion, inflammation, and direct renal injury. Early recognition and treatment are critical to prevent high mortality.

Multiple Myeloma: This condition can cause an increase in creatinine levels due to cast nephropathy or hypercalcemia-induced vasoconstriction in the kidneys.
Hemolytic-Uremic Syndrome (HUS) or Thrombotic Thrombocytopenic Purpura (TTP): These are rare conditions characterized by microangiopathic hemolytic anemia, thrombocytopenia, and AKI. They can present with a rise in creatinine levels and require prompt diagnosis and treatment to improve outcomes.