Do you deroof (de-roof) blisters in burn patients?

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Last updated: September 21, 2025View editorial policy

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Management of Burn Blisters

Burn blisters should not be deroofed but instead should be decompressed by piercing, leaving the blister roof intact to act as a biological dressing. 1, 2

Recommended Blister Management Protocol

  1. Initial Assessment:

    • Evaluate burn severity and extent (TBSA)
    • Identify if the burn involves face, hands, feet, genitalia (requires specialist referral)
    • Assess for signs of infection
  2. Blister Management Technique:

    • Gently cleanse the blister with antimicrobial solution, taking care not to rupture it 1
    • Pierce blister at the base with a sterile needle (bevel facing up) 1
    • Select a site where fluid will drain by gravity to discourage refilling 1
    • Apply gentle pressure with sterile gauze to facilitate drainage 1
    • Leave the blister roof intact as a biological dressing 1, 2
    • Cleanse again with antimicrobial solution after drainage 1
  3. Post-Drainage Care:

    • Apply a bland emollient (e.g., 50% white soft paraffin with 50% liquid paraffin) to support barrier function 1
    • Consider applying a non-adherent dressing if necessary 1
    • For large blisters, use a larger needle and pierce more than once to ensure adequate drainage 1

Rationale for Not Deroofing

The British Association of Dermatologists explicitly recommends against deroofing blisters 1. This approach is supported by several key benefits:

  1. Infection Prevention: The intact blister roof serves as a sterile biological dressing that protects the wound from contamination 2
  2. Pain Reduction: Keeping the roof intact reduces pain and discomfort 3
  3. Enhanced Healing: The blister fluid contains proteins and growth factors that may contribute to wound healing 4
  4. Reduced Scarring: Evidence suggests better cosmetic outcomes with intact blister roofs 3

Special Considerations

  • Pain Management: Offer analgesia prior to any blister procedure as many patients report pain or burning sensation during blister care 1
  • Documentation: Record the number and location of new blisters on a blister chart to track disease progress 1
  • Infection Monitoring: Vigilantly monitor for signs of infection, which is a significant risk and major cause of mortality 1, 5
  • Larger Blisters: Some research suggests that larger blisters (greater than the patient's little fingernail) may benefit from debriding while smaller ones should be left intact 6, but the most recent and highest quality guidelines still recommend keeping all blister roofs intact 1, 2

Infection Prevention

  • Daily washing with an antibacterial product to decrease colonization 1
  • Change dressings using aseptic technique 1
  • Consider barrier nursing for patients with extensive erosions 1
  • Obtain bacterial and viral swabs from erosions showing clinical signs of infection 1
  • Use systemic antibiotics only if there are clinical signs of infection 1, 5

The evidence strongly supports preserving the blister roof as a biological dressing while decompressing the fluid to relieve pressure and pain. This approach optimizes wound healing while minimizing infection risk and patient discomfort.

References

Guideline

Guideline Directed Topic Overview

Dr.Oracle Medical Advisory Board & Editors, 2025

Guideline

Management of Severe Burns

Praxis Medical Insights: Practical Summaries of Clinical Guidelines, 2025

Research

Role of Burn Blister Fluid in Wound Healing.

Journal of cutaneous and aesthetic surgery, 2021

Research

Management and prevention of drug resistant infections in burn patients.

Expert review of anti-infective therapy, 2019

Research

Treatment for burn blisters: debride or leave intact?

Emergency nurse : the journal of the RCN Accident and Emergency Nursing Association, 2014

Professional Medical Disclaimer

This information is intended for healthcare professionals. Any medical decision-making should rely on clinical judgment and independently verified information. The content provided herein does not replace professional discretion and should be considered supplementary to established clinical guidelines. Healthcare providers should verify all information against primary literature and current practice standards before application in patient care. Dr.Oracle assumes no liability for clinical decisions based on this content.

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