Calculating Doses from Retatrutide Vial
A 60mg vial of Retatrutide reconstituted with 3mL of bacteriostatic water will provide 30 weekly doses of 2mg each.
Calculation Explanation
When reconstituting a medication, the concentration is determined by dividing the total amount of active ingredient by the total volume of solution:
- Total drug amount: 60mg of Retatrutide
- Total volume after reconstitution: 3mL of bacteriostatic water
- Resulting concentration: 60mg ÷ 3mL = 20mg/mL
To calculate the number of doses:
- Desired dose: 2mg weekly
- Volume needed per dose: 2mg ÷ 20mg/mL = 0.1mL per dose
- Total number of doses: 3mL ÷ 0.1mL = 30 doses
Administration Guidelines
- Each 2mg dose requires withdrawing exactly 0.1mL of the reconstituted solution
- Use a calibrated insulin syringe with 0.01mL markings for accurate measurement
- Administer subcutaneously once weekly as indicated for Retatrutide
Storage Considerations
- After reconstitution, store the vial in the refrigerator (2-8°C or 36-46°F)
- Protect from light
- Use aseptic technique when withdrawing each dose
- The bacteriostatic water contains preservatives that help maintain sterility for multiple withdrawals
Common Pitfalls to Avoid
- Measurement errors: Using incorrect syringe types can lead to dosing inaccuracies
- Contamination: Always use sterile technique when accessing the vial
- Temperature fluctuations: Avoid freezing or exposing the reconstituted solution to high temperatures
- Air bubbles: Ensure all air bubbles are removed from the syringe before measuring the dose
This calculation provides a significant cost advantage compared to pre-filled pens, as one vial can supply approximately 7 months of weekly doses when properly stored and handled.