How is Basaglar (insulin glargine) administered via a Kiel-pen (insulin pen device)?

Basaglar Administration via KwikPen

Basaglar (insulin glargine) is administered subcutaneously once daily using the KwikPen device, which delivers precise doses through a push-button injection mechanism that requires proper technique to ensure accurate insulin delivery and optimal glycemic control. 1

KwikPen Device Features and Preparation

• The KwikPen is a prefilled, disposable insulin pen device that combines the insulin reservoir and injection mechanism in one unit
• Before first use:
  • Check that you have the correct insulin type (Basaglar/insulin glargine)
  • Store unused pens in the refrigerator (36-46°F/2-8°C)
  • Allow pen to reach room temperature before use (15-30 minutes) to minimize injection discomfort
  • Gently roll (do not shake) the pen between palms 10 times to mix the insulin 1

Administration Steps

1. Inspect the insulin: Ensure Basaglar appears clear and colorless; do not use if cloudy, colored, or contains particles
2. Attach a new needle: Always use a new sterile needle for each injection
3. Prime the pen: Perform a 2-unit safety test before each injection to ensure proper flow
4. Select the dose: Dial the prescribed number of units using the dose selector
5. Choose injection site: Rotate between abdomen, thigh, buttocks, or upper arm areas
6. Inject the insulin:
   • Clean the site with alcohol and let dry
   • Insert needle at 90° angle (may use 45° angle in thin patients)
   • Press injection button completely and hold for 5 seconds before removing needle 1
7. Dispose of needle: Safely remove and discard needle after each use

Dosing Considerations

• Basaglar is administered once daily at the same time each day
• The timing can be flexible but should be consistent from day to day
• Dose adjustments should be based on blood glucose monitoring results
• Unlike rapid-acting insulins, Basaglar is not meant to manage postprandial glucose spikes and may need to be supplemented with mealtime insulin 2, 3

Special Populations and Considerations

• For patients with visual impairment or dexterity issues, the KwikPen offers advantages over traditional syringes 1
• In obese, insulin-resistant patients, two separate daily doses may be more effective than a single large dose 2
• For children (≥6 years) with type 1 diabetes, the same administration technique applies 3

Common Pitfalls to Avoid

1. Improper storage: Storing in-use pens at temperatures above 86°F (30°C) or freezing the pen
2. Needle reuse: Reusing needles can cause painful injections and inaccurate dosing
3. Inadequate priming: Failure to prime before first use can lead to air bubbles and inaccurate dosing
4. Insufficient hold time: Not holding the injection button for 5 seconds can result in incomplete dosing
5. Lack of site rotation: Repeated injections in the same area can cause lipohypertrophy, affecting insulin absorption 1

Advantages of KwikPen Over Syringes

• More convenient and portable than vial and syringe
• Potentially more accurate dosing, especially for patients with visual or dexterity limitations
• Less visible and more discreet for public administration
• Eliminates the need to draw insulin from a vial 1

The proper administration of Basaglar via KwikPen is essential for achieving optimal glycemic control while minimizing the risk of hypoglycemia, which is the primary advantage of insulin glargine over older basal insulins 3, 4.