Retatrutide Reconstitution for 2mg Dose
To draw a 2mg dose of Retatrutide after reconstitution, you should add 6mL of bacteriostatic water to the 60mg powder vial, which will yield a concentration of 10mg/mL, allowing you to draw 0.2mL for a 2mg dose.
Reconstitution Calculation
When reconstituting medications, the key is to create a solution with a concentration that allows for accurate and practical dosing. For Retatrutide:
- Starting amount: 60mg powder
- Desired dose: 2mg
- Calculation process:
- If we add 6mL bacteriostatic water to 60mg powder:
- Concentration = 60mg ÷ 6mL = 10mg/mL
- To obtain 2mg: 2mg ÷ 10mg/mL = 0.2mL
This reconstitution approach creates a solution where each 0.1mL contains 1mg of Retatrutide, making it easy to measure precise doses with standard syringes.
Practical Considerations
- Use bacteriostatic water (containing 0.9% benzyl alcohol) rather than sterile water for injection when multiple doses will be drawn from the vial
- Ensure proper aseptic technique during reconstitution
- Gently swirl the vial to dissolve the powder completely - avoid shaking which can cause foaming
- Inspect the solution to ensure it is clear and free of particles before drawing your dose
Alternative Reconstitution Options
If different volumes of bacteriostatic water are used, the resulting concentrations would be:
- 3mL water → 20mg/mL (would require drawing 0.1mL for 2mg dose)
- 12mL water → 5mg/mL (would require drawing 0.4mL for 2mg dose)
The 6mL option provides a good balance between concentration and ease of measurement for the 2mg dose.
Storage After Reconstitution
- Store the reconstituted solution according to manufacturer's recommendations
- Label the vial with date and time of reconstitution
- Use aseptic technique when drawing subsequent doses
This reconstitution approach ensures accurate dosing while minimizing waste of this medication.