Calculating Retatrutide Doses from a Reconstituted Vial
When 3mL of bacteriostatic water is added to a 60mg powder vial of Retatrutide, a weekly 2mg dose using a U-100 syringe will provide 30 doses.
Calculation Process
To determine the number of doses available from a reconstituted vial of Retatrutide, we need to perform a simple concentration and dose calculation:
Determine the concentration after reconstitution:
- Total drug amount: 60mg Retatrutide powder
- Total volume after reconstitution: 3mL bacteriostatic water
- Concentration: 60mg ÷ 3mL = 20mg/mL
Calculate volume needed for each dose:
- Desired dose: 2mg weekly
- Volume per dose: 2mg ÷ 20mg/mL = 0.1mL
Calculate total number of doses:
- Total available volume: 3mL
- Volume per dose: 0.1mL
- Number of doses: 3mL ÷ 0.1mL = 30 doses
Practical Administration Using U-100 Insulin Syringe
When using a U-100 insulin syringe for administration:
- A U-100 syringe is calibrated where 100 units = 1mL
- For a 0.1mL dose (2mg of Retatrutide), you would draw up to the 10-unit mark on the U-100 syringe
Important Considerations
- Ensure proper sterile technique when reconstituting the medication
- Store the reconstituted medication according to manufacturer recommendations
- The bacteriostatic water preservative allows for multiple withdrawals from the same vial
- Label the reconstituted vial with the date of preparation
- Check for any particulate matter or discoloration before each use
This calculation demonstrates that a 60mg vial of Retatrutide reconstituted with 3mL of bacteriostatic water will provide 30 weekly doses at 2mg per dose, which can be accurately measured using a U-100 insulin syringe.