Specific Brands of Long-Acting and Short-Acting Inhalers
Long-acting and short-acting inhalers are available in various brand names with specific generic components, with combination products offering advantages in both maintenance and rescue therapy for respiratory conditions.
Short-Acting Inhalers (SABAs)
Short-Acting Beta-Agonists
- Ventolin HFA (albuterol)
- ProAir HFA (albuterol)
- Proventil HFA (albuterol)
- Xopenex (levalbuterol)
Short-Acting Muscarinic Antagonists
- Atrovent HFA (ipratropium bromide)
Combination Short-Acting Inhalers
- Combivent Respimat (ipratropium bromide/albuterol)
- DuoNeb (ipratropium bromide/albuterol) - nebulizer solution
Long-Acting Inhalers
Long-Acting Beta-Agonists (LABAs)
- Serevent Diskus (salmeterol)
- Foradil Aerolizer (formoterol)
- Perforomist (formoterol) - nebulizer solution
- Striverdi Respimat (olodaterol)
- Arcapta Neohaler (indacaterol)
Long-Acting Muscarinic Antagonists (LAMAs)
- Spiriva HandiHaler/Respimat (tiotropium)
- Tudorza Pressair (aclidinium)
- Incruse Ellipta (umeclidinium)
- Seebri Neohaler (glycopyrrolate)
ICS/LABA Combinations
- Symbicort (budesonide/formoterol) 1, 2
- Advair Diskus/HFA (fluticasone propionate/salmeterol) 3
- Dulera (mometasone/formoterol)
- Breo Ellipta (fluticasone furoate/vilanterol)
- Foster (beclometasone/formoterol) 3
LAMA/LABA Combinations
- Anoro Ellipta (umeclidinium/vilanterol)
- Stiolto Respimat (tiotropium/olodaterol)
- Utibron Neohaler (glycopyrrolate/indacaterol)
- Bevespi Aerosphere (glycopyrrolate/formoterol)
Triple Therapy (ICS/LABA/LAMA)
- Trelegy Ellipta (fluticasone furoate/umeclidinium/vilanterol)
- Breztri Aerosphere (budesonide/glycopyrrolate/formoterol)
Clinical Applications
Maintenance Therapy
- ICS/LABA combinations like Symbicort (budesonide/formoterol) are effective for maintenance therapy in asthma 1
- Some combinations can be used for both maintenance and rescue therapy, such as Symbicort SMART (Symbicort Maintenance And Reliever Therapy) 4, 5
- Combination therapies provide better asthma control than monotherapy with either component alone 6, 7
Rescue Therapy
- Short-acting beta-agonists like Ventolin are first-line for acute symptom relief 7
- For severe acute bronchospasm, adding ipratropium (Atrovent) to albuterol provides additive benefit 7
Dosing Considerations
- Budesonide/formoterol (Symbicort) has been shown to be effective in both once-daily and twice-daily dosing regimens 1, 2
- Adjustable maintenance dosing with budesonide/formoterol allows for equivalent or better asthma control with lower overall medication use compared to fixed dosing 1
Safety Considerations
- LABAs should never be used alone for asthma management due to increased risk of asthma-related death 7
- The combination of ICS with LABA reduces exacerbation rates compared to either component alone 6
- Budesonide/formoterol maintenance and reliever therapy (SMART) has been shown to reduce severe exacerbations compared to fixed-dose combination inhalers 5
This comprehensive list covers the major branded inhalers available for both maintenance and rescue therapy, with their generic components. Selection should be based on the specific respiratory condition, severity, and individual patient factors.