Differential Diagnosis for Tender Due to Moisture

• Single Most Likely Diagnosis
  • Intertrigo: This is the most likely diagnosis as it is a common condition characterized by inflammation of the skin folds due to moisture, friction, and bacterial or fungal infections, leading to tenderness.
• Other Likely Diagnoses
  • Contact Dermatitis: Moisture can exacerbate contact dermatitis, making the skin more prone to irritation and tenderness, especially in areas exposed to allergens or irritants.
  • Eczema (Atopic Dermatitis): While not exclusively caused by moisture, eczema can be worsened by excessive moisture, leading to increased tenderness and discomfort.
  • Folliculitis: This condition, involving inflammation of the hair follicles, can be caused by bacterial or fungal infections that thrive in moist environments, leading to tender skin.
• Do Not Miss Diagnoses
  • Cellulitis: Although less common, cellulitis is a serious bacterial infection of the skin that can be facilitated by moist conditions. It requires prompt antibiotic treatment to prevent serious complications.
  • Necrotizing Fasciitis: A rare but life-threatening condition that can arise from bacterial infections in moist environments. Early recognition and treatment are crucial to prevent high morbidity and mortality.
• Rare Diagnoses
  • Erythrasma: A superficial fungal infection that thrives in moist, occluded areas of the skin, leading to tender, well-demarcated patches.
  • Pitted Keratolysis: A condition caused by bacterial infection, characterized by tender, pitted lesions on the soles of the feet, often associated with excessive sweating and moisture.