What are the potential symptoms and treatment options for a patient with a C5-C6 diffuse disc bulge?

Medical Advisory BoardAll articles are reviewed for accuracy by our Medical Advisory Board
Educational purpose only • Exercise caution as content is pending human review
Article Review Status
Submitted
Under Review
Approved

Last updated: September 22, 2025View editorial policy

Personalize

Help us tailor your experience

Which best describes you? Your choice helps us use language that's most understandable for you.

Symptoms and Treatment Options for C5-C6 Diffuse Disc Bulge

A C5-C6 diffuse disc bulge commonly presents with neck pain, upper extremity radicular symptoms, and potential neurological deficits, requiring a stepped approach to treatment starting with conservative measures before considering surgical intervention in cases with progressive neurological deterioration.

Potential Symptoms

Neck-Related Symptoms

  • Neck pain, often with radiation to the shoulders
  • Limited cervical range of motion
  • Neck stiffness and muscle spasms
  • Pain exacerbated by certain neck movements or positions

Radicular Symptoms (C6 Nerve Root)

  • Radiating pain along the lateral aspect of the arm to the thumb and index finger
  • Numbness or tingling in the thumb, index finger, and lateral forearm
  • Weakness in the biceps and wrist extensors (C6 myotome)
  • Diminished biceps reflex 1

Neurological Symptoms

  • Potential weakness in upper extremity muscles (particularly biceps and wrist extensors)
  • Sensory disturbances in the C6 dermatome
  • In severe cases with significant cord compression:
    • Myelopathic signs (hyperreflexia, clonus, positive Hoffman's sign)
    • Gait disturbances
    • Hand coordination problems 2

Diagnostic Approach

Imaging

  • MRI of the cervical spine without IV contrast is the preferred initial imaging modality for patients with radiculopathy or myelopathy symptoms 2
  • Plain radiographs may show degenerative changes but are less sensitive for disc pathology
  • CT myelography may be considered if MRI is contraindicated or for presurgical planning 2

Treatment Options

Conservative Management (First-Line)

  1. Pain Management

    • NSAIDs for short-term pain relief (up to one week)
    • Muscle relaxants if muscle spasms are present 1
    • Avoid early opioid prescribing as recommended by CDC 1
  2. Physical Therapy

    • Active interventions focusing on cervical strengthening and stabilization
    • Postural education and ergonomic modifications
    • Range of motion exercises 1
  3. Non-Pharmacological Interventions

    • Heat therapy for muscle relaxation
    • Cognitive behavioral therapy for pain management
    • Activity modification while maintaining function 1

Interventional Procedures

  • Epidural steroid injections may be considered as a second-line treatment for persistent radicular pain 1
  • Cervical traction may provide temporary relief by increasing foraminal space 3

Surgical Intervention

Surgical treatment should be considered in the following circumstances:

  • Progressive neurological deficits
  • Severe or persistent radicular symptoms despite 6-12 weeks of conservative treatment
  • Evidence of myelopathy 2, 1

The most common surgical approaches include:

  • Anterior cervical discectomy and fusion (ACDF)
  • Cervical disc arthroplasty
  • Posterior cervical foraminotomy 2

Prognosis

The natural course of cervical disc pathology varies:

  • Many patients improve with conservative management
  • Disc bulges have a lower rate of spontaneous improvement (only about 3%) compared to protrusions (38%) and extrusions (75-100%) 4
  • Nerve root compromise may improve in 21-80% of cases depending on disc morphology 4

Important Considerations

Red Flags Requiring Urgent Evaluation

  • Signs of myelopathy (hyperreflexia, clonus, pathological reflexes)
  • Progressive neurological deficits
  • Bowel or bladder dysfunction (suggesting possible cauda equina syndrome) 2

Monitoring During Treatment

  • Regular assessment of neurological status
  • Evaluation of response to conservative measures
  • Consideration of electrophysiological monitoring if surgery is performed to minimize risk of neurological injury 2

Potential Complications of Untreated Severe Compression

  • Permanent neurological deficits
  • Development of myelopathy with long-term disability
  • Decreased quality of life and functional capacity 2

Conservative management should be the initial approach for most patients with C5-C6 disc bulge without severe neurological deficits, with surgical intervention reserved for cases with progressive neurological deterioration or failure of conservative measures after an adequate trial period.

References

Guideline

Pain Management Guidelines

Praxis Medical Insights: Practical Summaries of Clinical Guidelines, 2025

Guideline

Guideline Directed Topic Overview

Dr.Oracle Medical Advisory Board & Editors, 2025

Research

Chiropractic treatment of cervical radiculopathy caused by a herniated cervical disc.

Journal of manipulative and physiological therapeutics, 1994

Professional Medical Disclaimer

This information is intended for healthcare professionals. Any medical decision-making should rely on clinical judgment and independently verified information. The content provided herein does not replace professional discretion and should be considered supplementary to established clinical guidelines. Healthcare providers should verify all information against primary literature and current practice standards before application in patient care. Dr.Oracle assumes no liability for clinical decisions based on this content.

Have a follow-up question?

Our Medical A.I. is used by practicing medical doctors at top research institutions around the world. Ask any follow up question and get world-class guideline-backed answers instantly.