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Last updated: September 22, 2025View editorial policy

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Differential Diagnosis for Scalp Tenderness

Single Most Likely Diagnosis

  • Tension headache: This is often the most common cause of scalp tenderness, typically resulting from muscle tension in the neck and scalp.

Other Likely Diagnoses

  • Dermatitis or eczema: Skin conditions like dermatitis or eczema can cause inflammation and tenderness of the scalp.
  • Psoriasis: Scalp psoriasis can lead to redness, itching, and tenderness.
  • Folliculitis: An inflammation of the hair follicles, often due to infection, which can cause scalp tenderness.
  • Seborrheic dermatitis: A condition that can cause a red, itchy, and tender scalp.

Do Not Miss Diagnoses

  • Meningitis: Although less common, meningitis is a serious and potentially life-threatening condition that can cause scalp tenderness, along with other symptoms like fever, headache, and stiff neck.
  • Temporal arteritis: A condition where the blood vessels in the temples become inflamed, leading to scalp tenderness, especially in older adults.
  • Subgaleal hematoma: A collection of blood beneath the scalp, which can occur after a head injury and requires prompt medical attention.

Rare Diagnoses

  • Trichodynia: A condition characterized by pain or discomfort of the scalp, often associated with hair loss.
  • Lichen planopilaris: An inflammatory condition that leads to hair loss and can cause scalp tenderness.
  • Sarcoidosis: A rare disease that can cause inflammation in various parts of the body, including the scalp, leading to tenderness.
  • Cutaneous lymphoma: A type of cancer that affects the skin and can cause scalp tenderness among other symptoms.

Professional Medical Disclaimer

This information is intended for healthcare professionals. Any medical decision-making should rely on clinical judgment and independently verified information. The content provided herein does not replace professional discretion and should be considered supplementary to established clinical guidelines. Healthcare providers should verify all information against primary literature and current practice standards before application in patient care. Dr.Oracle assumes no liability for clinical decisions based on this content.

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