Restorolax (Polyethylene Glycol) Dosing for a 10-Month-Old
For a 10-month-old infant, the recommended dose of Restorolax (polyethylene glycol 3350) is 0.78 g/kg/day.
Evidence-Based Dosing Recommendation
Research specifically examining PEG use in infants under 18 months found that:
- The mean effective maintenance dose was 0.78 g/kg/day (range: 0.26-1.26 g/kg/day) 1
- This dosage was found to be safe and effective in 97.6% of infants studied
- The study included infants as young as 0-5 months
Administration Guidelines
- The powder should be fully dissolved in liquid before administration
- For infants, the dose can be mixed with formula, breast milk, or water
- Ensure complete dissolution before giving to the infant
- Divide the daily dose into 1-2 administrations for better tolerance
Safety Considerations
- PEG without electrolytes (hypotonic PEG) is generally preferred for pediatric patients
- Monitor for potential side effects:
- Transient diarrhea (occurred in some infants but resolved with dose adjustment) 1
- Increased gas
- Abdominal discomfort
Important Precautions
- The FDA label for polyethylene glycol states "children 16 years of age or under: ask a doctor" 2, highlighting the importance of medical supervision
- Do not use for more than 7 days without medical reassessment
- If symptoms worsen or do not improve after 3 days, consult a healthcare provider
- Do not combine with starch-based thickeners used for difficult swallowing
Clinical Monitoring
- Monitor stool consistency and frequency
- If diarrhea occurs, reduce the dose and reassess
- Ensure adequate hydration is maintained
- If constipation persists despite treatment, further evaluation may be needed to rule out underlying conditions
This dosing recommendation is based on research specifically studying PEG use in infants under 18 months, which demonstrated both safety and efficacy at the recommended dose of 0.78 g/kg/day.