What is the most common complication after parotid (salivary gland) surgery or parotidectomy?

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Most Common Complication After Parotid Surgery or Parotidectomy

The most common complication after parotid surgery or parotidectomy is skin flap anesthesia (option C), which affects approximately 71% of patients following the procedure. 1

Complications of Parotidectomy: Frequency and Impact

Parotid surgery is associated with several potential complications that can significantly impact patients' quality of life. The three main complications mentioned in the question occur at different frequencies:

  1. Skin Flap Anesthesia (71%) - This is the most common complication, characterized by numbness in the skin around the surgical site due to damage to the greater auricular nerve 1. This high prevalence makes it the correct answer to the question.

  2. Facial Nerve Palsy (38-40%) - Temporary facial weakness occurs in approximately 27% of cases, with permanent facial weakness occurring in about 2.5% of patients who had normal preoperative function 2. An older study reported temporary facial nerve palsy in 38% of cases and permanent palsy in 9% 3.

  3. Frey's Syndrome (28-62%) - This condition, characterized by gustatory sweating (sweating while eating), has a variable reported incidence. One study found that 62% of patients suffered from gustatory sweating following superficial parotidectomy 4, while another reported a clinical incidence of 28% 1. Interestingly, subclinical Frey's syndrome may be present in up to 85% of patients who don't report symptoms 4.

Risk Factors and Prevention

Several factors influence the risk of complications after parotidectomy:

  • Extent of Surgery: More extensive procedures carry higher complication risks. The risk ratios for developing Frey's syndrome increase progressively from lumpectomy to total parotidectomy 5.

  • Surgical Technique: Maintaining thick skin flaps when oncologically appropriate can reduce the risk of complications such as Frey's syndrome 2.

  • Tumor Characteristics: Patients with superficial T1 or T2 low-grade tumors may be candidates for partial superficial excision, which can reduce complication risks 2.

  • Preventive Measures: Free abdominal fat grafting has been associated with a lower incidence of Frey's syndrome 1.

Management of Complications

For patients experiencing these complications:

  • Skin Flap Anesthesia: This typically improves over time but may be permanent in some cases. Patient education about this common complication is important.

  • Facial Nerve Palsy: Temporary weakness usually resolves within weeks to months. Physical therapy and eye protection may be needed during recovery.

  • Frey's Syndrome: Intracutaneous injection of botulinum toxin A is an effective, long-lasting, and well-tolerated treatment that can be repeated if symptoms recur 2, 4.

Clinical Implications

When counseling patients about parotid surgery, it's important to discuss all potential complications, with particular emphasis on skin flap anesthesia given its high frequency. While First Bite Syndrome appears to have a greater impact on quality of life than both Frey's syndrome and skin flap anesthesia 1, the latter remains the most common postoperative complication that patients will experience.

Surgeons should consider the extent of surgery carefully, as more limited procedures may be appropriate for benign conditions to reduce complication rates 3.

References

Research

Frey Syndrome, First Bite Syndrome, great auricular nerve morbidity, and quality of life following parotidectomy.

European archives of oto-rhino-laryngology : official journal of the European Federation of Oto-Rhino-Laryngological Societies (EUFOS) : affiliated with the German Society for Oto-Rhino-Laryngology - Head and Neck Surgery, 2018

Guideline

Surgical Management of Salivary Gland Tumors

Praxis Medical Insights: Practical Summaries of Clinical Guidelines, 2025

Research

Complications of parotid surgery: the need for selectivity.

The British journal of surgery, 1989

Research

[Frey syndrome after lateral parotidectomy. Follow-up and therapeutic outlook].

Mund-, Kiefer- und Gesichtschirurgie : MKG, 2001

Research

Frey syndrome: factors influencing the time to event.

International journal of oral and maxillofacial surgery, 2015

Professional Medical Disclaimer

This information is intended for healthcare professionals. Any medical decision-making should rely on clinical judgment and independently verified information. The content provided herein does not replace professional discretion and should be considered supplementary to established clinical guidelines. Healthcare providers should verify all information against primary literature and current practice standards before application in patient care. Dr.Oracle assumes no liability for clinical decisions based on this content.

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