What is the treatment for peroneal tendonitis?

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Treatment for Peroneal Tendonitis

The most effective treatment for peroneal tendonitis is a comprehensive rehabilitation program including NSAIDs for pain relief, eccentric strengthening exercises, and functional support, while avoiding immobilization and limiting corticosteroid injections. 1

Initial Conservative Management (0-4 weeks)

Pain Control

  • NSAIDs:
    • Ibuprofen 1.2g daily initially, can be increased to 2.4g daily if needed
    • Naproxen 500mg twice daily is an alternative option
    • May be combined with paracetamol (up to 4g daily) for enhanced pain relief 1

Activity Modification

  • Avoid activities that exacerbate symptoms
  • Protected range of motion exercises
  • Avoid complete immobilization as it may lead to stiffness 1

Physical Therapy

  • Gentle stretching exercises
  • Ice application for 15-20 minutes several times daily
  • Functional support with a brace or taping may help reduce pain during activities 1

Intermediate Phase (4-8 weeks)

Progressive Rehabilitation

  • Eccentric strengthening exercises targeting the peroneal muscles
  • Proprioceptive and balance training
  • Gradual increase in weight-bearing activities 1

Manual Therapy

  • Lateral calcaneal glide technique has shown effectiveness in some cases 2
  • Mobilization of hypomobile talocrural joint if present 2

Advanced Phase (8-12 weeks)

Functional Rehabilitation

  • Occupation-specific training
  • Sport-specific exercises if applicable
  • Functional exercises that mimic daily activities 1

Injection Therapy

Corticosteroid Injections

  • Consider only if conservative measures fail after 4-6 weeks
  • Limited use recommended (2-3 injections, 4-6 weeks between injections)
  • Provides short-term relief but does not change long-term outcomes 1
  • Ultrasound-guided peroneal tendon sheath corticosteroid injection has shown to be relatively safe and effective, with 36.8% of patients experiencing pain relief for more than 12 weeks 3

Injection Technique

  • Must be performed using aseptic technique
  • Ultrasound guidance improves accuracy and safety
  • Avoid injection if there are signs of infection at the site 1

Diagnostic Imaging

  • Ultrasound has shown 100% sensitivity and 90% accuracy in diagnosing peroneal tendon tears
  • MRI can be used with reported sensitivities and specificities of 83.9% and 74.5% for tendinopathy 1
  • Note that MRI findings should be interpreted carefully as up to 34% of asymptomatic patients may have peroneus brevis tendon tears 1

Surgical Intervention

  • Consider only when conservative measures fail after 3-6 months of well-managed treatment 1
  • Indications include:
    • Persistent pain and dysfunction despite appropriate conservative management
    • Peroneal tendon tears involving >50% of the tendon (tenodesis recommended)
    • Tears involving <50% of the tendon (primary repair and tubularization) 4
    • Peroneal tendon subluxation requiring repair or reconstruction of the superior peroneal retinaculum 4

Return to Activity Criteria

  • Complete resolution of pain
  • Full range of motion
  • Strength symmetry >90% compared to the uninjured side
  • Successful completion of occupation-specific functional tests 1

Follow-up Schedule

  • Regular assessment at 2,6, and 12 weeks to evaluate:
    • Pain levels
    • Range of motion
    • Functional improvement
    • Signs of recurrent instability 1

Common Pitfalls and Caveats

  • Peroneal tendinopathy is often underdiagnosed and should be considered in all cases of chronic lateral ankle pain 5
  • Avoid overuse of corticosteroid injections as they may weaken tendons and lead to rupture
  • Patients with hindfoot varus may require additional interventions such as valgus osteotomy to address biomechanical factors 5
  • Don't rely solely on imaging findings, as asymptomatic individuals may have abnormal MRI findings 1
  • Failure to address underlying biomechanical issues may lead to recurrence

References

Guideline

Injection Therapy Guidelines

Praxis Medical Insights: Practical Summaries of Clinical Guidelines, 2025

Research

Operative treatment for peroneal tendon disorders.

The Journal of bone and joint surgery. American volume, 2008

Research

The surgical treatment of peroneal tendinopathy (excluding subluxations): a series of 17 patients.

The Journal of foot and ankle surgery : official publication of the American College of Foot and Ankle Surgeons, 2012

Professional Medical Disclaimer

This information is intended for healthcare professionals. Any medical decision-making should rely on clinical judgment and independently verified information. The content provided herein does not replace professional discretion and should be considered supplementary to established clinical guidelines. Healthcare providers should verify all information against primary literature and current practice standards before application in patient care. Dr.Oracle assumes no liability for clinical decisions based on this content.

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