What is the protocol for a needle stick injury?

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Last updated: September 23, 2025View editorial policy

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Needle Stick Injury Protocol

Immediate management of a needle stick injury requires washing the wound with soap and water, reporting the incident, assessing the source patient's infection status, and initiating appropriate post-exposure prophylaxis within 24 hours of exposure. 1

Immediate Steps After Needle Stick Injury

  1. Wound Care:

    • Wash the injury site thoroughly with soap and water
    • Do not squeeze or scrub the wound
    • If mucous membrane exposure occurred (eyes, mouth), flush with water or saline
  2. Report the Incident:

    • Notify supervisor immediately
    • Complete an incident report form documenting:
      • Type of injury
      • Type of needle used
      • Procedure being performed
      • Details of exposure (depth, visible blood, etc.)
  3. Source Patient Assessment:

    • Identify the source patient if possible
    • Test source patient for HBsAg, HCV antibody, and HIV (with consent)
    • Assess risk factors if source is unknown

Risk Assessment

The risk of transmission varies by pathogen:

  • Hepatitis B: Up to 30% without prophylaxis if source is e-antigen positive
  • Hepatitis C: Approximately 1.8%
  • HIV: Approximately 0.3% 1

Higher risk exposures include:

  • Hollow-bore needles (higher risk than solid needles)
  • Deep punctures
  • Visible blood on device
  • Needle placed directly in patient's vein or artery

Post-Exposure Prophylaxis (PEP)

For Hepatitis B Exposure:

If exposed person is unvaccinated and source is HBsAg-positive:

  • Administer Hepatitis B Immune Globulin (HBIG) 0.06 mL/kg IM immediately (within 24 hours if possible)
  • Initiate HBV vaccine series 1, 2

If exposed person is vaccinated:

  • Test for anti-HBs antibodies
  • If inadequate antibody levels (<10 SRU), administer HBIG immediately plus HBV vaccine booster 2

For HIV Exposure:

If source patient is HIV positive or unknown with high-risk factors:

  • Initiate antiretroviral prophylaxis preferably within first 24 hours
  • Basic regimen: 2 anti-HIV drugs for low-risk exposures
  • Expanded regimen: 3 anti-HIV drugs for high-risk exposures 1

For Hepatitis C Exposure:

  • No proven post-exposure prophylaxis
  • Monitor for early detection of infection to allow prompt treatment

Follow-up Testing and Monitoring

  1. Baseline Testing:

    • Test exposed person for HBV, HCV, and HIV at baseline
  2. Follow-up Testing:

    • Follow-up testing at 6 weeks, 3 months, and 6 months
    • Additional testing at 12 months for HIV if source patient had HIV
  3. Counseling:

    • Provide counseling about preventing transmission during follow-up period
    • Discuss symptoms of viral hepatitis and HIV seroconversion

Prevention Strategies

Healthcare facilities should implement:

  • Comprehensive prevention programs
  • Staff education on safe practices
  • Use of safer medical devices with engineered safety features
  • Proper sharps disposal (containers placed close to use areas, never overfilled)
  • Never recap, bend, or break needles 1

Common Pitfalls to Avoid

  • Delayed reporting: Effectiveness of PEP decreases significantly after 24-48 hours
  • Inadequate source patient testing: Failure to test source patients can lead to unnecessary PEP or missed opportunities for prevention
  • Improper wound care: Aggressive wound scrubbing can increase tissue trauma and potentially enhance viral entry
  • Incomplete follow-up: Missing follow-up appointments can lead to delayed diagnosis of transmitted infections
  • Recapping needles: This practice significantly increases risk of injury and should never be done 1

By following this protocol promptly and thoroughly, healthcare workers can significantly reduce the risk of infection transmission following needle stick injuries.

References

Guideline

Needle Stick Injury Management

Praxis Medical Insights: Practical Summaries of Clinical Guidelines, 2025

Professional Medical Disclaimer

This information is intended for healthcare professionals. Any medical decision-making should rely on clinical judgment and independently verified information. The content provided herein does not replace professional discretion and should be considered supplementary to established clinical guidelines. Healthcare providers should verify all information against primary literature and current practice standards before application in patient care. Dr.Oracle assumes no liability for clinical decisions based on this content.

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