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Last updated: September 23, 2025View editorial policy

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Differential Diagnosis for Glass on Foot

  • Single most likely diagnosis:
    • Laceration: This is the most likely diagnosis because stepping on glass is a common cause of cuts and lacerations on the foot. The sharp edges of the glass can easily penetrate the skin, leading to bleeding and potential infection.
  • Other Likely diagnoses:
    • Puncture wound: Similar to a laceration, a puncture wound can occur if the glass penetrates the skin deeply but with a smaller entry point. This type of wound can be particularly prone to infection.
    • Foreign body: If a piece of glass remains in the foot after the initial injury, it can cause ongoing pain, infection, or other complications until it is removed.
  • Do Not Miss diagnoses:
    • Tetanus infection: Although not immediately life-threatening, tetanus infection can occur if the wound becomes contaminated with tetanus spores, especially in individuals who are not up to date with their tetanus vaccinations.
    • Osteomyelitis or septic arthritis: If the glass penetrates deeply into the foot, it could introduce bacteria into the bone or joint, leading to serious infections like osteomyelitis or septic arthritis, which require prompt medical attention.
  • Rare diagnoses:
    • Nerve or tendon damage: Depending on the depth and location of the glass injury, there is a possibility of damaging nerves or tendons in the foot, which could lead to long-term functional impairments.
    • Infection with specific pathogens: While rare, stepping on contaminated glass could potentially introduce specific pathogens into the wound, such as MRSA (methicillin-resistant Staphylococcus aureus), which would require targeted antibiotic treatment.

Professional Medical Disclaimer

This information is intended for healthcare professionals. Any medical decision-making should rely on clinical judgment and independently verified information. The content provided herein does not replace professional discretion and should be considered supplementary to established clinical guidelines. Healthcare providers should verify all information against primary literature and current practice standards before application in patient care. Dr.Oracle assumes no liability for clinical decisions based on this content.

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