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Last updated: September 23, 2025View editorial policy

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Differential Diagnosis for Floating Stool

  • Single most likely diagnosis
    • Malabsorption (e.g., celiac disease, pancreatic insufficiency): Floating stool is often associated with malabsorption of fats, which can lead to an increase in gas production and a decrease in stool density, causing it to float.
  • Other Likely diagnoses
    • Gastrointestinal infection (e.g., giardiasis): Certain infections can lead to malabsorption and gas production, resulting in floating stool.
    • Lactose intolerance or other carbohydrate malabsorption: Undigested carbohydrates can be fermented by colonic bacteria, producing gas and leading to floating stool.
    • Small intestine bacterial overgrowth (SIBO): Excessive bacterial growth in the small intestine can lead to malabsorption and gas production.
  • Do Not Miss (ddxs that may not be likely, but would be deadly if missed.)
    • Intestinal obstruction or ileus: Although less common, floating stool can be a sign of an underlying obstruction or ileus, which requires prompt medical attention.
    • Inflammatory bowel disease (e.g., Crohn's disease, ulcerative colitis): These conditions can cause malabsorption, diarrhea, and floating stool, and require timely diagnosis and treatment.
  • Rare diagnoses
    • Whipple's disease: A rare bacterial infection that can cause malabsorption and floating stool.
    • Short bowel syndrome: A condition characterized by a significant loss of intestinal tissue, leading to malabsorption and potentially floating stool.
    • Carcinoid syndrome: A rare condition caused by a neuroendocrine tumor, which can lead to diarrhea and floating stool due to the production of vasoactive peptides.

Professional Medical Disclaimer

This information is intended for healthcare professionals. Any medical decision-making should rely on clinical judgment and independently verified information. The content provided herein does not replace professional discretion and should be considered supplementary to established clinical guidelines. Healthcare providers should verify all information against primary literature and current practice standards before application in patient care. Dr.Oracle assumes no liability for clinical decisions based on this content.

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