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Last updated: September 23, 2025View editorial policy

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Differential Diagnosis for Upper Abdominal Protrusion

  • Single Most Likely Diagnosis
    • Obesity: The most common cause of upper abdominal protrusion, due to excess fat accumulation in the abdominal region.
  • Other Likely Diagnoses
    • Pregnancy: Uterine expansion during pregnancy can cause the abdomen to protrude.
    • Ascites: Accumulation of fluid in the peritoneal cavity, often due to liver disease, can lead to abdominal distension.
    • Gastrointestinal obstruction: Blockage of the intestine can cause abdominal swelling and protrusion.
    • Hernias (e.g., hiatal, epigastric, or umbilical): Weakening of the abdominal wall can allow organs to bulge through, causing protrusion.
  • Do Not Miss Diagnoses
    • Abdominal aortic aneurysm: A life-threatening condition where the aorta enlarges, which can cause abdominal protrusion and pain.
    • Ovarian cyst or tumor: Large ovarian cysts or tumors can cause abdominal distension and protrusion.
    • Liver or spleen enlargement: Conditions such as liver disease or splenomegaly can cause the abdomen to protrude.
  • Rare Diagnoses
    • Neurofibromatosis: A genetic disorder that can cause abdominal tumors and protrusion.
    • Prune belly syndrome: A rare congenital disorder characterized by abdominal muscle weakness and protrusion.
    • Desmoid tumor: A rare type of tumor that can occur in the abdominal wall and cause protrusion.

Professional Medical Disclaimer

This information is intended for healthcare professionals. Any medical decision-making should rely on clinical judgment and independently verified information. The content provided herein does not replace professional discretion and should be considered supplementary to established clinical guidelines. Healthcare providers should verify all information against primary literature and current practice standards before application in patient care. Dr.Oracle assumes no liability for clinical decisions based on this content.

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