Medical Advisory BoardAll articles are reviewed for accuracy by our Medical Advisory Board
Educational purpose only • Exercise caution as content is pending human review
Article Review Status
Submitted
Under Review
Approved

Last updated: September 23, 2025View editorial policy

Personalize

Help us tailor your experience

Which best describes you? Your choice helps us use language that's most understandable for you.

Differential Diagnosis for Testicular Pain in a 78-year-old Male

Single Most Likely Diagnosis

  • Epididymitis: Although the patient denies dysuria, epididymitis can occur without urinary symptoms, especially in older adults. The presence of hyaline and granular casts in the urine may indicate a urinary tract issue that could be related to or exacerbate epididymitis.

Other Likely Diagnoses

  • Orchitis: Inflammation of one or both testicles, which could be due to viral or bacterial infection. The absence of dysuria does not rule out orchitis, as it can be caused by non-sexually transmitted infections.
  • Testicular Torsion: Although less common in older adults, testicular torsion is a possibility, especially if the patient has a history of testicular abnormalities. It is characterized by severe pain and requires immediate medical attention.
  • Prostatitis: Given the patient's age and the presence of urinary casts, prostatitis (inflammation of the prostate) could be a contributing factor to testicular pain, especially if the prostate is enlarged or infected.

Do Not Miss Diagnoses

  • Testicular Cancer: While less likely to present with acute pain, testicular cancer can cause discomfort or pain and is crucial not to miss due to its potential for cure with early detection.
  • Aortic Aneurysm or Aortic Dissection: These conditions can refer pain to the testicles and are life-threatening. Although the patient denies flank pain, the possibility of an aortic issue should be considered, especially in an older adult.
  • Renal Infarction: Could potentially cause referred pain to the testicles and is a serious condition that requires prompt diagnosis and treatment.

Rare Diagnoses

  • Henoch-Schönlein Purpura (HSP): A form of vasculitis that can cause testicular pain among other symptoms. It's more common in children but can occur in adults.
  • Polyarteritis Nodosa (PAN): A systemic vasculitis that can affect various parts of the body, including the testicles, causing pain.
  • Spermatic Cord Torsion: A rare condition where the spermatic cord becomes twisted, cutting off the blood supply to the testicle. It's more common in younger men but can occur at any age.

Professional Medical Disclaimer

This information is intended for healthcare professionals. Any medical decision-making should rely on clinical judgment and independently verified information. The content provided herein does not replace professional discretion and should be considered supplementary to established clinical guidelines. Healthcare providers should verify all information against primary literature and current practice standards before application in patient care. Dr.Oracle assumes no liability for clinical decisions based on this content.

Have a follow-up question?

Our Medical A.I. is used by practicing medical doctors at top research institutions around the world. Ask any follow up question and get world-class guideline-backed answers instantly.