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Differential Diagnosis for Burning at the Glans Penis

Single Most Likely Diagnosis

  • Urinary Tract Infection (UTI): This is often the most common cause of burning sensations at the glans penis, especially if the patient experiences dysuria (painful urination) or frequent urination. The burning sensation can be due to the infection causing inflammation of the urethra.

Other Likely Diagnoses

  • Sexually Transmitted Infections (STIs): Infections like gonorrhea, chlamydia, and herpes can cause burning sensations at the glans penis. These infections often present with additional symptoms such as discharge, lesions, or systemic symptoms like fever.
  • Balanitis: An inflammation of the glans penis, which can be caused by poor hygiene, infections (fungal, bacterial), or irritants. It presents with redness, swelling, and sometimes a foul odor, along with a burning sensation.
  • Urethritis: Inflammation of the urethra, which can be caused by infections or irritants, leading to a burning sensation during urination.

Do Not Miss Diagnoses

  • Cancer of the Penis: Although rare, penile cancer can present with a variety of symptoms including a burning sensation, especially if there is an ulcerative lesion. Early detection is crucial for effective treatment.
  • Syphilis: A systemic STI that can have a wide range of presentations, including a painless chancre in the primary stage, which might be perceived as a burning sensation in some cases.

Rare Diagnoses

  • Lichen Sclerosus: A chronic inflammatory skin condition that can affect the genital area, leading to itching, burning, and sometimes pain. It's more common in uncircumcised males.
  • Peyronie's Disease: Characterized by the formation of fibrous scar tissue inside the penis, leading to curved, painful erections. The pain can sometimes be perceived as a burning sensation.
  • Neurological Conditions: Certain conditions like neuropathy or nerve damage can cause abnormal sensations, including burning, in the genital area. These are less common causes of burning at the glans penis.

Professional Medical Disclaimer

This information is intended for healthcare professionals. Any medical decision-making should rely on clinical judgment and independently verified information. The content provided herein does not replace professional discretion and should be considered supplementary to established clinical guidelines. Healthcare providers should verify all information against primary literature and current practice standards before application in patient care. Dr.Oracle assumes no liability for clinical decisions based on this content.

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