Medical Advisory BoardAll articles are reviewed for accuracy by our Medical Advisory Board
Educational purpose only • Exercise caution as content is pending human review
Article Review Status
Submitted
Under Review
Approved

Last updated: September 24, 2025View editorial policy

Personalize

Help us tailor your experience

Which best describes you? Your choice helps us use language that's most understandable for you.

Differential Diagnosis for Pain in SI Joint after Fall with Negative Imaging

  • Single most likely diagnosis
    • Ligamentous sprain or strain: The most common cause of pain in the SI joint after a fall, especially with negative imaging, is a ligamentous sprain or strain. The SI joint is supported by strong ligaments, and a fall can cause stretching or tearing of these ligaments, leading to pain and inflammation.
  • Other Likely diagnoses
    • Sacroiliac joint dysfunction: This refers to any condition that affects the normal functioning of the SI joint, including abnormal movement or malalignment, which can cause pain.
    • Muscle strain: The muscles around the SI joint, such as the gluteals and piriformis, can be strained during a fall, leading to pain in the area.
    • Bursitis: Inflammation of the bursae around the SI joint can cause pain, especially if the bursae are irritated or inflamed due to the fall.
  • Do Not Miss (ddxs that may not be likely, but would be deadly if missed.)
    • Fracture not visible on initial imaging: Although initial imaging may be negative, it's crucial to consider the possibility of a fracture that may not be immediately visible, such as a stress fracture or a small avulsion fracture.
    • Infection or osteomyelitis: Infection in the SI joint or the surrounding bone can cause severe pain and has the potential for serious complications if not promptly treated.
    • Cauda equina syndrome: Although rare, a fall can potentially cause nerve compression or damage leading to cauda equina syndrome, a serious condition that requires immediate medical attention.
  • Rare diagnoses
    • Sacroiliac joint infection: This is a rare condition where the SI joint becomes infected, often due to bacterial or fungal causes.
    • Tumor or metastasis: In rare cases, pain in the SI joint could be due to a primary tumor or metastasis to the area, which would require further investigation.
    • Spondyloarthritis: Conditions like ankylosing spondylitis can cause inflammation and pain in the SI joint, although these conditions typically have a more gradual onset and are associated with other systemic symptoms.

Professional Medical Disclaimer

This information is intended for healthcare professionals. Any medical decision-making should rely on clinical judgment and independently verified information. The content provided herein does not replace professional discretion and should be considered supplementary to established clinical guidelines. Healthcare providers should verify all information against primary literature and current practice standards before application in patient care. Dr.Oracle assumes no liability for clinical decisions based on this content.

Have a follow-up question?

Our Medical A.I. is used by practicing medical doctors at top research institutions around the world. Ask any follow up question and get world-class guideline-backed answers instantly.