Medical Advisory BoardAll articles are reviewed for accuracy by our Medical Advisory Board
Educational purpose only • Exercise caution as content is pending human review
Article Review Status
Submitted
Under Review
Approved

Last updated: September 24, 2025View editorial policy

Personalize

Help us tailor your experience

Which best describes you? Your choice helps us use language that's most understandable for you.

Differential Diagnosis for Right Lower Quadrant Abdominal Pain in a 32-Year-Old Male

Single Most Likely Diagnosis

  • Appendicitis: This is the most common cause of right lower quadrant abdominal pain in young adults. The pain often starts near the navel and then moves to the right lower quadrant. Appendicitis is an emergency that requires prompt surgical intervention.

Other Likely Diagnoses

  • Gastroenteritis: Inflammation of the stomach and intestines, usually due to a viral or bacterial infection, can cause abdominal pain, nausea, vomiting, and diarrhea. The pain can be localized to the right lower quadrant.
  • Intestinal Obstruction: A blockage in the small or large intestine can cause severe abdominal pain, nausea, vomiting, and constipation. The pain can be localized to the right lower quadrant if the obstruction is in the ileum or cecum.
  • Inflammatory Bowel Disease (IBD): Conditions like Crohn's disease or ulcerative colitis can cause chronic abdominal pain, diarrhea, and weight loss. The pain can be localized to the right lower quadrant if the disease affects the terminal ileum or cecum.
  • Ovarian Torsion (less likely in males but can occur in cases of testicular torsion or other testicular issues): While less common in males, testicular torsion can cause severe pain in the lower abdomen, which might be referred to the right lower quadrant.

Do Not Miss Diagnoses

  • Ectopic Pregnancy (in cases of intersex individuals or those with a female reproductive system): Although extremely rare in a genetically male individual, it's crucial to consider in individuals with a female reproductive system or those with a disorder of sex development. Ectopic pregnancy is a life-threatening condition that requires immediate medical attention.
  • Ruptured Viseral Aneurysm: A rupture of an aneurysm in the visceral arteries can cause severe abdominal pain, hypotension, and shock. This is a rare but life-threatening condition.
  • Diverticulitis: Inflammation of a diverticulum in the colon can cause severe abdominal pain, usually in the left lower quadrant, but can occasionally be in the right lower quadrant if the diverticulum is in the cecum or ascending colon.
  • Mesenteric Ischemia: A reduction in blood flow to the intestines can cause severe abdominal pain, nausea, vomiting, and bloody stools. This condition requires prompt diagnosis and treatment to prevent intestinal infarction.

Rare Diagnoses

  • Meckel's Diverticulum: A congenital anomaly of the small intestine can cause abdominal pain, nausea, vomiting, and gastrointestinal bleeding if it becomes inflamed or obstructed.
  • Right Lower Quadrant Hematoma: A collection of blood in the right lower quadrant can cause abdominal pain and is often due to trauma or a bleeding disorder.
  • Carcinoid Tumor: A rare tumor of the neuroendocrine system can cause abdominal pain, flushing, diarrhea, and wheezing. These tumors are often found in the small intestine and can cause right lower quadrant pain if they are located in the ileum.
  • Intussusception: A condition where a part of the intestine telescopes into another part can cause severe abdominal pain, vomiting, and bloody stools. This condition is more common in children but can occur in adults.

Professional Medical Disclaimer

This information is intended for healthcare professionals. Any medical decision-making should rely on clinical judgment and independently verified information. The content provided herein does not replace professional discretion and should be considered supplementary to established clinical guidelines. Healthcare providers should verify all information against primary literature and current practice standards before application in patient care. Dr.Oracle assumes no liability for clinical decisions based on this content.

Have a follow-up question?

Our Medical A.I. is used by practicing medical doctors at top research institutions around the world. Ask any follow up question and get world-class guideline-backed answers instantly.