Chronic Myeloid Leukemia (CML): This condition is characterized by the overproduction of granulocytes, including eosinophils, basophils, and monocytes, leading to an elevated white blood cell count. Microcytic anemia can also be present due to bone marrow infiltration by leukemic cells or due to associated iron deficiency.

Myeloproliferative Neoplasm (MPN): Conditions like Polycythemia Vera, Essential Thrombocythemia, and Primary Myelofibrosis can present with elevated counts of various cell lines, including eosinophils, basophils, and monocytes, along with anemia.
Chronic Eosinophilic Leukemia (CEL): Characterized by a marked and persistent eosinophilia, which can lead to elevated white cell counts and may be associated with microcytic anemia.
Hypereosinophilic Syndrome (HES): Although primarily known for eosinophilia, some forms can present with increases in other cell lines and anemia.

Acute Myeloid Leukemia (AML): AML can present with a wide range of blood abnormalities, including elevated eosinophils, basophils, and monocytes, along with anemia. It is crucial to diagnose AML promptly due to its aggressive nature and the need for immediate treatment.
Systemic Mastocytosis: This condition can lead to an increase in basophils and sometimes eosinophils, along with anemia. It's critical to consider due to its potential for severe allergic reactions and organ damage.

Mast Cell Leukemia: An extremely rare condition that can present with elevated basophils and eosinophils, along with other systemic symptoms.
Eosinophilic Granuloma with Leukemic Transformation: Part of the spectrum of Langerhans cell histiocytosis, which can rarely transform into a leukemic phase, presenting with elevated eosinophils and other abnormalities.
Myelodysplastic Syndromes (MDS): Some subtypes of MDS can present with increases in eosinophils, basophils, and monocytes, along with microcytic anemia, although this is less common.