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Differential Diagnosis for Pediatric Bumps on Hands and Feet

Single Most Likely Diagnosis

  • Molluscum contagiosum: This is a common, benign viral infection that causes small, pearly, or flesh-colored bumps on the skin. It's highly contagious and often seen in children, making it a likely diagnosis for bumps on the hands and feet.

Other Likely Diagnoses

  • Warts: Caused by the human papillomavirus (HPV), warts are another common skin condition in children that can appear on the hands and feet. They are contagious and can be spread by direct contact.
  • Eczema (Dyshidrotic): This condition leads to small, itchy blisters on the hands and feet, especially in children. It's associated with atopic dermatitis and can be triggered by allergies or irritants.
  • Keratosis pilaris: A harmless condition that causes small, rough patches on the skin, often on the hands and feet. It's more common in children and can be associated with dry skin.

Do Not Miss Diagnoses

  • Hand, Foot, and Mouth Disease (HFMD): Although it often presents with additional symptoms like fever and mouth sores, HFMD can sometimes be mistaken for other conditions. It's crucial to diagnose promptly due to its contagious nature and potential for outbreaks.
  • Cellulitis: A bacterial skin infection that can cause redness, swelling, and warmth in the affected area. It requires prompt antibiotic treatment to prevent serious complications.
  • Tinea infections (Ringworm): Fungal infections that can affect the skin on the hands and feet, causing circular, itchy lesions. They are contagious and require antifungal treatment.

Rare Diagnoses

  • Pitted keratolysis: A rare bacterial infection that causes small pits or bumps on the soles of the feet or, less commonly, the palms of the hands. It's associated with excessive sweating and warm environments.
  • Keratoacanthoma: A rare, benign tumor that can appear as a firm, round bump on the skin, including the hands and feet. It often resolves on its own but can be similar in appearance to more serious conditions.
  • Epidermoid cysts: Rarely, bumps on the hands and feet could be epidermoid cysts, which are benign cysts that can appear anywhere on the skin. They are usually harmless but can become inflamed or infected.

Professional Medical Disclaimer

This information is intended for healthcare professionals. Any medical decision-making should rely on clinical judgment and independently verified information. The content provided herein does not replace professional discretion and should be considered supplementary to established clinical guidelines. Healthcare providers should verify all information against primary literature and current practice standards before application in patient care. Dr.Oracle assumes no liability for clinical decisions based on this content.

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