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Differential Diagnosis

The patient's symptoms of burning, redness, and hair shedding localized to the back of the head and crown area, along with a positive scalp KOH prep, suggest a fungal infection. The lack of improvement with fluconazole and the request for terbinafine indicate a possible dermatophyte infection. Here are the differential diagnoses categorized:

  • Single most likely diagnosis
    • Tinea capitis (Dermatophyte infection): The positive KOH prep and the patient's symptoms are consistent with a dermatophyte infection, which is commonly treated with terbinafine. The lack of response to fluconazole, which is more effective against yeast infections, further supports this diagnosis.
  • Other Likely diagnoses
    • Candidiasis: Although the patient did not respond to fluconazole, candidiasis is still a possibility, especially if the strain is resistant to fluconazole. However, the presentation is less typical for candidiasis.
    • Seborrheic dermatitis: This condition can cause redness and hair shedding, but the positive KOH prep and the specific localization to the back of the head and crown area make it less likely.
  • Do Not Miss (ddxs that may not be likely, but would be deadly if missed.)
    • Kerion: A severe form of tinea capitis that can cause significant inflammation and scarring. It requires prompt treatment to prevent long-term hair loss.
    • Majocchi's granuloma: A deep dermatophyte infection that can cause granulomatous lesions. It is less common but can be severe if left untreated.
  • Rare diagnoses
    • Fungal folliculitis: An infection of the hair follicles caused by fungi, which can present with similar symptoms.
    • White piedra: A superficial fungal infection of the hair shaft, which can cause hair shedding and redness. However, it is less common and typically does not cause burning sensations.

Professional Medical Disclaimer

This information is intended for healthcare professionals. Any medical decision-making should rely on clinical judgment and independently verified information. The content provided herein does not replace professional discretion and should be considered supplementary to established clinical guidelines. Healthcare providers should verify all information against primary literature and current practice standards before application in patient care. Dr.Oracle assumes no liability for clinical decisions based on this content.

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