From the Research
T3 toxicosis can potentially increase susceptibility to recurrent upper respiratory infections with persistent cough due to its impact on the immune system and respiratory function. This condition, also known as triiodothyronine toxicosis, is characterized by excessive levels of T3 thyroid hormone in the body, leading to a hypermetabolic state that can weaken immune responses and make individuals more vulnerable to infections, including those affecting the upper respiratory tract 1. The most recent and highest quality study on the management of thyrotoxicosis, including T3 toxicosis, is the 2016 American Thyroid Association Guidelines, which provides evidence-based recommendations for the diagnosis and management of hyperthyroidism and other causes of thyrotoxicosis 1. Some key points to consider include:
- The hypermetabolic state caused by excess thyroid hormones can lead to increased stress on the body, potentially weakening immune responses and making individuals more susceptible to infections.
- Thyroid dysfunction can cause changes in respiratory muscle function and may contribute to persistent cough symptoms.
- If experiencing recurrent respiratory infections and symptoms like unexplained weight loss, heat intolerance, anxiety, rapid heartbeat, or tremors, consultation with a healthcare provider for proper evaluation is necessary.
- Treatment typically involves medications like methimazole or propylthiouracil to reduce thyroid hormone production, and addressing the underlying cause of the thyroid dysfunction, as recommended by the American Thyroid Association guidelines 1. It is essential to manage the thyroid condition effectively to reduce susceptibility to infections and improve overall immune function, as highlighted in the guidelines and supported by studies such as the one on transient T3 toxicosis associated with Hashimoto's disease 2.