Dry Eye Syndrome: This condition is a common cause of eye pain without signs of infection or inflammation like pink eye, sty, conjunctivitis, or blepharitis. It occurs due to insufficient lubrication of the eyes, leading to discomfort and pain.

Acute Angle-Closure Glaucoma: Although less common, this condition can cause severe eye pain and is often accompanied by blurred vision and headache. It's a medical emergency but doesn't typically present with the excluded conditions.
Optic Neuritis: Inflammation of the optic nerve can cause eye pain, especially with movement of the eye, and is not associated with the excluded conditions.
Sinusitis: Referral pain from sinus infections can cause eye pain without any signs of local eye infection or inflammation.

Migraine or Cluster Headaches: These can cause severe eye pain and are critical to diagnose due to their impact on quality of life and potential for treatment.
Temporal Arteritis: This condition, although rare, can cause eye pain and is a medical emergency due to the risk of vision loss if not promptly treated.
Endophthalmitis: A severe inflammation of the interior of the eye, usually caused by infection. It's a medical emergency and can lead to blindness if not treated promptly.

Scleritis: Inflammation of the sclera (the white part of the eye), which can cause severe eye pain and is often described as deep or boring.
Uveitis: Inflammation of the uvea, the middle layer of the eye, which can cause eye pain, sensitivity to light, and vision problems.
Trigeminal Neuralgia: A chronic pain condition that affects the trigeminal nerve, which can cause intense shock-like or stabbing pain in parts of the face, including the eyes.