What is the recommended treatment for an infected pinna?

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Last updated: September 25, 2025View editorial policy

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Treatment of Infected Pinna

Topical fluoroquinolone ear drops (such as ciprofloxacin 0.2% or ofloxacin 0.3%) are the first-line treatment for infected pinna, with cure rates of 77-96%. 1

Diagnosis and Assessment

An infected pinna typically presents with:

  • Tenderness of the pinna that is often intense and disproportionate to visual inspection
  • Erythema and edema of the pinna
  • Possible cellulitis extending to adjacent skin
  • May be associated with ear canal inflammation in cases of otitis externa

Treatment Algorithm

First-Line Treatment

  • Topical fluoroquinolone ear drops 1
    • Ciprofloxacin 0.2% or ofloxacin 0.3%
    • Adults and children ≥13 years: 10 drops once daily for 7 days
    • Children 6 months to 13 years: 5 drops once daily for 7 days
    • Complete the full 7-day course even if symptoms improve earlier

Administration Technique

  • Clean the ear canal of any debris or discharge before administering drops
  • Tilt the patient's head and "pump" the tragus several times after instilling drops to aid medication delivery 1
  • For adherent discharge, use cotton-tipped swab with hydrogen peroxide (safe with tympanostomy tubes) 2

Pain Management

  • Acetaminophen or NSAIDs for immediate pain relief until the infection is controlled
  • Pain typically improves within 48 hours of starting treatment 1

Special Considerations

For Pseudomonas Infections

  • Pseudomonas aeruginosa is a common causative organism in pinna perichondritis, especially with piercing-related infections 3
  • Ensure the selected antibiotic has anti-pseudomonal activity

For Severe or Complicated Infections

If any of the following are present, systemic antibiotics are indicated 2:

  • Cellulitis extending beyond the pinna to adjacent skin
  • High fever (≥38.5°C/101.3°F)
  • Severe pain or systemic symptoms
  • Immunocompromised state
  • Failure to respond to topical therapy after 72 hours

Systemic Antibiotic Options

For cellulitis of the pinna with systemic signs of infection 2:

  • Clindamycin: 600-900 mg every 6 hours IV (adults); 10-13 mg/kg every 8 hours IV (children)
  • Cefazolin: 1 g every 8 hours IV (adults); 33 mg/kg/dose (children)

Monitoring and Follow-up

  • Reassess after 72 hours of therapy to evaluate response 1

  • If no improvement is seen after 72 hours, reevaluate and consider:

    • Obtaining cultures
    • Changing antibiotic therapy
    • Referral to an otolaryngologist
  • If the patient fails to respond after 7 days, refer to an otolaryngologist for:

    • Microscopic examination
    • Culture of ear drainage
    • Evaluation for possible complications or alternative diagnoses 1

Prevention of Recurrence

  • Avoid excessive moisture in the ear canal
  • Dry ears thoroughly after water exposure
  • Consider prophylactic acidifying solutions after water exposure
  • Avoid trauma from inappropriate cleaning (don't insert cotton-tipped swabs into ear canal) 1

Important Cautions

  • Avoid neomycin-containing products as first-line therapy as they can cause sensitization in 5-15% of patients 1
  • Do not use aminoglycoside-containing eardrops due to potential ototoxicity 2
  • Using oral antibiotics for uncomplicated cases results in lower cure rates, more systemic side effects, and contributes to antibiotic resistance 1
  • Consider rare causes such as monkeypox in patients with auricular perichondritis who have systemic symptoms 4

References

Guideline

Treatment of Localized Ear Infections

Praxis Medical Insights: Practical Summaries of Clinical Guidelines, 2025

Guideline

Guideline Directed Topic Overview

Dr.Oracle Medical Advisory Board & Editors, 2025

Professional Medical Disclaimer

This information is intended for healthcare professionals. Any medical decision-making should rely on clinical judgment and independently verified information. The content provided herein does not replace professional discretion and should be considered supplementary to established clinical guidelines. Healthcare providers should verify all information against primary literature and current practice standards before application in patient care. Dr.Oracle assumes no liability for clinical decisions based on this content.

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