What is the recommended dose of Tylenol (acetaminophen) for a 2-month-old infant weighing 6.03 kg, using an 80 mg/ml concentration?

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Last updated: September 25, 2025View editorial policy

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Acetaminophen Dosing for a 2-Month-Old Infant

The recommended acetaminophen dose for a 6.03 kg 2-month-old infant using an 80 mg/ml concentration is 0.75 ml (60 mg) every 4-6 hours as needed, not to exceed 5 doses in 24 hours.

Dosage Calculation

The appropriate dosing for acetaminophen (Tylenol) in infants is weight-based:

  • Standard dosing: 10-15 mg/kg/dose every 4-6 hours as needed
  • For this 6.03 kg infant:
    • Minimum dose (10 mg/kg): 60.3 mg
    • Maximum dose (15 mg/kg): 90.45 mg
    • Recommended dose: 60 mg (approximately 10 mg/kg)

Administration using 80 mg/ml concentration:

  • Dose calculation: 60 mg ÷ 80 mg/ml = 0.75 ml

Important Considerations

  • Always use the measuring device provided with the medication for accurate dosing
  • Do not exceed 5 doses in 24 hours
  • Wait at least 4 hours between doses
  • For infants under 3 months with fever, medical evaluation is recommended before administering acetaminophen

Safety Precautions

  • Double-check the concentration (80 mg/ml) before administering
  • Store medication out of reach of children
  • Do not administer with other medications containing acetaminophen to avoid overdose
  • Contact a healthcare provider if:
    • Fever persists more than 3 days
    • Pain persists more than 5 days
    • Symptoms worsen or new symptoms develop

Alternative Options

  • For infants with fever, non-pharmacological measures like maintaining hydration and appropriate clothing are important
  • For infants over 12 months, honey (2.5-5 ml) may help with cough symptoms, but should NEVER be given to infants under 12 months due to risk of botulism 1

Remember that acetaminophen is generally considered safe when used at appropriate doses, but overdosing can lead to serious hepatotoxicity. Always verify dosing with a healthcare provider if uncertain.

References

Guideline

Cough Management in Children

Praxis Medical Insights: Practical Summaries of Clinical Guidelines, 2025

Professional Medical Disclaimer

This information is intended for healthcare professionals. Any medical decision-making should rely on clinical judgment and independently verified information. The content provided herein does not replace professional discretion and should be considered supplementary to established clinical guidelines. Healthcare providers should verify all information against primary literature and current practice standards before application in patient care. Dr.Oracle assumes no liability for clinical decisions based on this content.

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