What is the cause of nystagmus in a 98-year-old female with a history of right-sided Cerebrovascular Accident (CVA)?

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Differential Diagnosis for 98 year old female with right eye nystagmus and past medical history of right sided CVA

  • Single most likely diagnosis
    • Stroke (specifically, a sequela of the previous right sided CVA): The patient's history of a right sided CVA increases the likelihood that the nystagmus is related to a stroke, possibly due to damage in the brainstem or cerebellum.
  • Other Likely diagnoses
    • Vestibular disorder (e.g., labyrinthitis, vestibular neuritis): These conditions can cause nystagmus and are relatively common in the elderly population.
    • Cerebellar ataxia: Given the patient's age and history of CVA, cerebellar ataxia is a possible cause of nystagmus.
    • Multiple sclerosis: Although less likely in a 98-year-old, multiple sclerosis can cause nystagmus and should be considered, especially if there are other neurological symptoms.
  • Do Not Miss diagnoses
    • Brain tumor (e.g., cerebellar or brainstem tumor): Although rare, a brain tumor could cause nystagmus and would be critical to diagnose due to its potential impact on treatment and prognosis.
    • Wernicke's encephalopathy: This condition, caused by thiamine deficiency, can lead to nystagmus and is potentially life-threatening if not treated promptly.
    • Posterior circulation stroke: A new stroke in the posterior circulation could cause nystagmus and is a critical diagnosis to consider due to its potential for severe consequences.
  • Rare diagnoses
    • Spinocerebellar ataxia: A group of genetic disorders that can cause cerebellar ataxia and nystagmus, although unlikely in a new presentation at 98 years old.
    • Creutzfeldt-Jakob disease: A rare, degenerative neurological disorder that can cause nystagmus, although it would be unusual in this clinical context.
    • Superior oblique myokymia: A rare condition characterized by intermittent, involuntary contractions of the superior oblique muscle, leading to nystagmus.

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This information is intended for healthcare professionals. Any medical decision-making should rely on clinical judgment and independently verified information. The content provided herein does not replace professional discretion and should be considered supplementary to established clinical guidelines. Healthcare providers should verify all information against primary literature and current practice standards before application in patient care. Dr.Oracle assumes no liability for clinical decisions based on this content.

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