Robitussin (Dextromethorphan) Dosage Instructions
For optimal treatment of cough, Robitussin (dextromethorphan) should be dosed according to age, with adults taking 10 mL every 12 hours, not exceeding 20 mL in 24 hours. 1
Dosage Guidelines by Age
Adults and children 12 years and older:
- 10 mL every 12 hours
- Do not exceed 20 mL in 24 hours
Children 6 to under 12 years:
- 5 mL every 12 hours
- Do not exceed 10 mL in 24 hours
Children 4 to under 6 years:
- 2.5 mL every 12 hours
- Do not exceed 5 mL in 24 hours
Children under 4 years:
- Do not use
Administration Instructions
- Shake the bottle well before each use
- Use only the dosing cup provided with the medication
- Do not use this dosing cup with other products
- For maximum effectiveness, take as directed and do not exceed recommended dosage
Clinical Efficacy and Safety
Dextromethorphan is one of the most widely used non-opioid cough suppressants available over-the-counter 2. While it has been in use for more than 30 years with a generally favorable safety profile, clinical evidence for its efficacy in acute upper respiratory tract infections is limited 3.
Adverse reactions are infrequent and usually not severe, primarily consisting of neurological, cardiovascular, and gastrointestinal disturbances that are typically dose-related 4. The safety profile is particularly reassuring regarding overdose in both adults and children, though the medication should always be used as directed.
Important Precautions
- Do not combine with monoamine oxidase inhibitors (MAOIs) as this can lead to serious adverse reactions 4
- Store medication out of reach of children
- Discontinue use and consult a healthcare provider if cough persists for more than 7 days, recurs frequently, or is accompanied by fever, rash, or persistent headache
- Be aware that dextromethorphan has potential for abuse 4
Measuring Technique
For accurate dosing:
- Place the dosing cup on a flat surface
- Pour medication to the appropriate line marking
- Ensure you're viewing the cup at eye level to confirm accurate measurement
- Administer the medication
- Rinse the cup after each use
Following these instructions will help ensure safe and effective use of Robitussin (dextromethorphan) for cough relief.