How is botulinum toxin (Botox) used to treat a lower lid jelly roll under the eyes?

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Botulinum Toxin Treatment for Lower Lid Jelly Roll

Botulinum toxin is not recommended for treating lower lid jelly roll under the eyes as this condition requires volume replacement rather than muscle paralysis, and misuse could lead to serious complications including eyelid malposition and dry eye syndrome.

Understanding Lower Lid Jelly Roll

Lower lid jelly roll refers to a bulge or fullness in the lower eyelid area that creates a visible roll or fold. This is primarily caused by:

  • Fat protrusion or pseudoherniation
  • Fluid retention
  • Loss of skin elasticity
  • Weakening of orbital septum

Why Botulinum Toxin Is Not Appropriate

Botulinum toxin works by inhibiting acetylcholine release at the neuromuscular junction, causing muscle paralysis 1. However, this mechanism is not suitable for treating lower lid jelly roll because:

  1. The condition is structural rather than muscular in nature
  2. Weakening the orbicularis oculi muscle in this area could worsen the condition
  3. Risk of complications outweighs potential benefits

Potential Complications of Botulinum Toxin in Lower Lid

Using botulinum toxin in the lower eyelid area carries significant risks:

  • Eyelid malposition (ectropion)
  • Incomplete eye closure
  • Dry eye syndrome
  • Increased risk of corneal exposure
  • Lower eyelid edema
  • Smile asymmetry
  • Incomplete sphincter function 2

Appropriate Uses of Botulinum Toxin Around Eyes

While not appropriate for jelly roll correction, botulinum toxin can be used in the periocular area for:

  • Lateral canthal rhytides (crow's feet)
  • Mild widening of palpebral aperture
  • Improvement of dynamic wrinkles 3

When used in the lower eyelid for appropriate indications:

  • Lower doses (2-4 units) are recommended 2
  • Precise injection technique is critical
  • Injections should be placed 3mm below ciliary margin 3
  • Combined treatment with lateral orbital area produces synergistic effects

Alternative Treatments for Lower Lid Jelly Roll

More appropriate treatments include:

  1. Dermal fillers - For volume replacement
  2. Blepharoplasty - Surgical removal of excess fat/skin
  3. Laser resurfacing - For skin tightening
  4. Radiofrequency treatments - For tissue tightening
  5. Topical treatments - For mild cases (retinoids, peptides)

Important Considerations for Periocular Botulinum Toxin Use

If botulinum toxin is used in the periocular region for other indications:

  • Use minimum effective dose
  • Apply precise injection technique
  • Avoid massaging treated area after injection
  • Keep patient upright for 3-4 hours post-treatment 4
  • Have epinephrine and antihistamines available (1-2% risk of anaphylaxis) 4
  • Consider pain management techniques (topical anesthetics, cooling) 4

Anatomical Considerations

The lower face and periocular region have complex muscular anatomy:

  • Muscles are in close proximity
  • They interface at different levels and depths
  • They perform heterogeneous functions 5

This complexity requires precise knowledge of functional anatomy to avoid complications when using botulinum toxin in this region.

In conclusion, botulinum toxin is not the appropriate treatment for lower lid jelly roll. Structural correction through fillers, surgery, or other modalities would provide more effective and safer results for this condition.

References

Research

Botulinum toxin.

Indian journal of dermatology, 2010

Research

Botulinum A toxin (BOTOX) in the lower eyelid: dose-finding study.

Dermatologic surgery : official publication for American Society for Dermatologic Surgery [et al.], 2003

Research

Botulinum-A toxin treatment of the lower eyelid improves infraorbital rhytides and widens the eye.

Dermatologic surgery : official publication for American Society for Dermatologic Surgery [et al.], 2001

Guideline

Botulism

Praxis Medical Insights: Practical Summaries of Clinical Guidelines, 2025

Research

Anatomy of the Lower Face and Botulinum Toxin Injections.

Plastic and reconstructive surgery, 2015

Professional Medical Disclaimer

This information is intended for healthcare professionals. Any medical decision-making should rely on clinical judgment and independently verified information. The content provided herein does not replace professional discretion and should be considered supplementary to established clinical guidelines. Healthcare providers should verify all information against primary literature and current practice standards before application in patient care. Dr.Oracle assumes no liability for clinical decisions based on this content.

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