What is the primary cause of infection from dog and cat bites?

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Infection Caused by Dog and Cat Bites

Pasteurella species are the primary cause of infection from dog and cat bites. 1, 2, 3

Microbiology of Animal Bite Infections

Dog Bites

  • Pasteurella canis is the most common pathogen isolated from dog bite infections 1
  • Approximately 20-30% of dog bite wounds contain Pasteurella species 4
  • Other common organisms include:
    • Staphylococcus species
    • Streptococcus species
    • Capnocytophaga canimorsus
    • Various anaerobes

Cat Bites

  • Pasteurella multocida is found in over 50% of infected cat bite wounds 4, 5
  • Cat bites have a significantly higher infection rate (20-80%) compared to dog bites (3-18%) 2
  • Studies have shown approximately 90% carriage rate of P. multocida in the oral cavity of domestic cats 2

Clinical Presentation and Complications

  • Pasteurella infections typically present with:

    • Rapid onset of cellulitis at the bite site
    • Development within 12-24 hours after injury
    • Serosanguineous or purulent drainage
    • Lymphangitis 3
  • Potential complications include:

    • Deep tissue infection
    • Osteomyelitis
    • Septic arthritis (particularly with bites near joints)
    • Systemic infections in immunocompromised patients 3

Other Potential Pathogens

While Pasteurella species are the predominant cause, other pathogens may be involved:

  • Staphylococcus aureus (including MRSA in some cases)
  • Streptococcus species
  • Capnocytophaga canimorsus (can cause severe sepsis)
  • Moraxella species
  • Anaerobic bacteria (present in approximately one-third of bite wounds) 1, 6, 5

Treatment Considerations

  • Penicillin and its derivatives remain the treatment of choice for Pasteurella infections 2, 3
  • Amoxicillin-clavulanate is recommended for empiric treatment of dog and cat bite wounds to cover both Pasteurella and other potential pathogens 4
  • High antibiotic susceptibility has been observed for benzylpenicillin (100%), amoxicillin-clavulanate (100%), cefazolin (98.37%), and azithromycin (94.02%) against P. multocida 2

Common Pitfalls in Management

  • Underestimating the severity of cat bites, which have higher infection rates than dog bites
  • Failing to consider Pasteurella as the primary pathogen, which requires appropriate antibiotic coverage
  • Delaying treatment, as Pasteurella infections can progress rapidly
  • Inadequate wound cleansing and debridement, which are essential components of management
  • Not considering tetanus prophylaxis when indicated

In conclusion, while animal bites can introduce various pathogens including Staphylococcus aureus, Mycobacterium, Actinomyces, and Candida, Pasteurella species are clearly the predominant causative organisms in infections resulting from dog and cat bites.

References

Guideline

Guideline Directed Topic Overview

Dr.Oracle Medical Advisory Board & Editors, 2025

Research

Management of cat and dog bites.

American family physician, 1995

Research

Bite wounds and infection.

Clinical infectious diseases : an official publication of the Infectious Diseases Society of America, 1992

Research

Bite-related and septic syndromes caused by cats and dogs.

The Lancet. Infectious diseases, 2009

Professional Medical Disclaimer

This information is intended for healthcare professionals. Any medical decision-making should rely on clinical judgment and independently verified information. The content provided herein does not replace professional discretion and should be considered supplementary to established clinical guidelines. Healthcare providers should verify all information against primary literature and current practice standards before application in patient care. Dr.Oracle assumes no liability for clinical decisions based on this content.

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