Steroid Injection for Poison Ivy Treatment
For severe poison ivy dermatitis, a single intramuscular injection of a long-acting corticosteroid such as triamcinolone acetonide (40-60 mg) is the recommended treatment option when systemic therapy is indicated. 1
Treatment Algorithm for Poison Ivy
First-Line Management:
Immediate decontamination:
- Wash exposed areas with soap and water or commercial decontamination product as soon as possible 1
- Effectiveness decreases rapidly: 100% at immediate contact, 50% at 10 minutes, 25% at 15 minutes, 10% at 30 minutes
Mild to moderate cases:
When to Consider Systemic Steroids:
- Extensive rash (>20% body surface area)
- Facial or genital involvement
- Severe symptoms not responding to topical treatment
- Significant impact on activities of daily living
Systemic Steroid Options:
Option 1: Steroid Injection
- Medication: Triamcinolone acetonide 40-60 mg IM injection
- Advantages: Single administration, good compliance, rapid onset
- Disadvantages: Cannot be titrated once administered
Option 2: Oral Prednisone
- Regimen:
- Long course (preferred): 40 mg daily for 5 days, followed by taper over 10 days (total 15 days) 2
- Short course: 40 mg daily for 5 days (higher risk of rebound)
- Evidence: Longer course reduces need for additional medications (NNT = 3) 2
- Warning: Short-duration oral corticosteroids (<14 days) are associated with increased risk of return visits 3
Important Considerations
Efficacy and Duration
- Poison ivy dermatitis typically lasts 1-3 weeks if untreated 4
- Systemic steroids should be administered for at least 14 days (including taper) to prevent rebound dermatitis 3
- Emergency physicians often prescribe shorter courses (1-13 days) in 86% of cases, which is associated with higher return visit rates 3
Contraindications and Cautions
- Uncontrolled diabetes
- Active infection
- Immunocompromised status
- Peptic ulcer disease
- Pregnancy (relative contraindication)
Monitoring and Follow-up
- Reassess after 2 weeks if symptoms persist or worsen 1
- Monitor for steroid-related side effects (mood changes, insomnia, increased appetite)
- Consider referral to dermatology if no improvement after systemic therapy
Prevention Strategies
- Avoidance of Toxicodendron plants
- Protective clothing when in high-risk areas
- Barrier creams before potential exposure 5
- Immediate washing with soap and water after suspected exposure 1
Remember that the extent and severity of symptoms are proportional to the area and duration of exposure, with approximately 50-75% of individuals reacting to urushiol, the allergic compound in poison ivy 1.