From the Guidelines
Concerta typically works for about 10-12 hours after taking a single dose. This extended-release methylphenidate medication is designed to provide day-long coverage for ADHD symptoms with once-daily dosing. The medication uses a unique osmotic release system (OROS) that gradually releases the active ingredient throughout the day, providing an initial release followed by steady delivery over several hours, as noted in a study published in the Journal of the American Academy of Child and Adolescent Psychiatry 1. This allows for consistent symptom control throughout the school or work day without requiring multiple doses.
Key Points
- The duration of action may vary slightly between individuals based on metabolism, body weight, and other factors.
- Some people might experience effects for slightly shorter or longer periods.
- Concerta is usually taken in the morning to ensure the medication's effects align with daytime activities and to prevent potential sleep disturbances if taken too late in the day.
- If you find the medication wearing off too early or lasting too long, consult your healthcare provider about adjusting the dosage or timing. The study published in 2002 1 highlights the effectiveness of Concerta as a useful alternative to older stimulant medications, providing equally effective results as immediate-release methylphenidate tablets given three times daily.
From the FDA Drug Label
The FDA drug label does not answer the question.
From the Research
Duration of Action of Concerta (Methylphenidate)
- The duration of action of Concerta (methylphenidate) is approximately 12 hours, as stated in studies 2, 3, 4.
- This long-acting formulation is designed to provide continuous coverage throughout the day, eliminating the need for multiple daily doses 5, 3.
- Clinical trials have shown that Concerta has a continued action over a 12-hour period, making it an effective treatment for attention-deficit hyperactivity disorder (ADHD) 3, 4.
- The 12-hour duration of action of Concerta allows for once-daily dosing, which can improve adherence to medication and reduce stigma associated with taking medication at school or work 2, 5.
- Studies have also demonstrated that Concerta's effects last into the evening, as measured by parent ratings, making it a suitable treatment option for parents who desire medication benefits for their child throughout the day and early evening 4.