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Differential Diagnosis for Epididymitis and Inflamed Penis and Testicle

Single Most Likely Diagnosis

  • Epididymo-orchitis: This condition is an inflammation of both the epididymis and testis, often caused by bacterial infection, which can lead to symptoms such as pain, swelling, and inflammation of the testicle and epididymis. The involvement of both the epididymis and testicle, along with the symptoms described, makes this the most likely diagnosis.

Other Likely Diagnoses

  • Urinary Tract Infection (UTI): A UTI can lead to epididymitis, especially if the infection spreads from the urinary tract to the epididymis. Symptoms can include pain, burning during urination, and frequent urination.
  • Sexually Transmitted Infections (STIs): Certain STIs, such as chlamydia and gonorrhea, can cause epididymitis and inflammation of the penis and testicle. These infections are common in sexually active individuals and can present with symptoms like discharge, pain, and inflammation.
  • Orchitis: Inflammation of one or both testicles, usually caused by bacterial or viral infections. It can present with testicular pain, swelling, and inflammation.

Do Not Miss Diagnoses

  • Testicular Torsion: A medical emergency where the spermatic cord becomes twisted, cutting off the blood supply to the testicle. It requires immediate attention to save the testicle and can present with sudden, severe testicular pain, swelling, and elevation of the testicle.
  • Fournier's Gangrene: A rare but serious condition characterized by necrotizing fasciitis of the genitalia, which can lead to severe pain, swelling, and potentially life-threatening complications if not promptly treated.

Rare Diagnoses

  • Henoch-Schönlein Purpura (HSP): A form of vasculitis that can affect various parts of the body, including the testicles, leading to inflammation and pain. It's more common in children but can occur in adults.
  • Behçet's Disease: A rare disorder that causes blood vessel inflammation throughout the body, which can lead to a variety of symptoms including genital ulcers and inflammation.
  • Mumps Orchitis: A viral infection that can cause inflammation of the testicles, typically occurring in individuals who have not been vaccinated against mumps.

Professional Medical Disclaimer

This information is intended for healthcare professionals. Any medical decision-making should rely on clinical judgment and independently verified information. The content provided herein does not replace professional discretion and should be considered supplementary to established clinical guidelines. Healthcare providers should verify all information against primary literature and current practice standards before application in patient care. Dr.Oracle assumes no liability for clinical decisions based on this content.

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