What are the discharge instructions for a 60-year-old male with a corneal abrasion who will be prescribed antibiotic eyedrops, such as moxifloxacin (moxifloxacin) or ofloxacin (ofloxacin)?

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Discharge Instructions for Corneal Abrasion with Antibiotic Eyedrops

For a 60-year-old male with a corneal abrasion, instill antibiotic eyedrops (such as moxifloxacin) 3 times daily for 7 days until complete healing occurs, and use preservative-free lubricants every 2 hours to promote healing. 1, 2

Medication Administration Instructions

  • Antibiotic eyedrops:

    • Moxifloxacin 0.5%: Apply 1 drop to the affected eye 3 times daily for 7 days 1
    • Ofloxacin 0.3%: Apply 1 drop to the affected eye 4 times daily for 7 days 3
    • Wash hands thoroughly before and after applying drops
    • Do not touch the tip of the dropper to any surface, including the eye
    • Wait at least 5 minutes between different eye medications
  • Preservative-free lubricants:

    • Apply preservative-free artificial tears every 2 hours to maintain corneal moisture and promote healing 2
    • Use more frequently if the eye feels dry or irritated

Pain Management

  • Take oral analgesics as needed for pain (acetaminophen or NSAIDs) 2
  • Avoid rubbing the eye as this may worsen the abrasion
  • A cold compress may help reduce discomfort and swelling

Activity Restrictions

  • Avoid wearing contact lenses until the cornea is completely healed and your doctor approves
  • Wear protective eyewear during the day to prevent accidental rubbing
  • Consider wearing an eye shield at night to prevent accidental trauma during sleep
  • Avoid swimming and hot tubs until the abrasion is completely healed
  • Avoid dusty or smoky environments that may irritate the eye

Follow-up Instructions

  • Return for follow-up evaluation in 24 hours if:
    • The abrasion is large (>4mm)
    • Pain or symptoms worsen
    • Vision deteriorates
    • There is increased redness, discharge, or light sensitivity 4, 2
  • Complete healing typically occurs within 24-72 hours for small abrasions

Warning Signs (Seek Immediate Medical Attention)

  • Worsening pain despite medication
  • Decreased or blurred vision
  • Increased redness or swelling
  • Yellow or green discharge
  • Lack of improvement within 48 hours 4
  • Development of a white spot on the cornea (may indicate infection)

Prevention of Future Injuries

  • Wear protective eyewear during high-risk activities (sports, yard work, construction)
  • Avoid rubbing eyes when they feel irritated
  • Use appropriate eye protection in dusty or debris-filled environments 2

Important Considerations

  • Antibiotic drops help prevent infection but may cause mild stinging upon application
  • Some patients may experience mild itching or discomfort from the antibiotic drops 3
  • Rarely, corneal deposits can form with prolonged use of moxifloxacin, so adhere to the prescribed duration 5
  • The evidence for antibiotic use in corneal abrasions is of low to very low certainty, but it remains standard practice to prevent potential infection 6
  • Treatment should be continued until complete healing is achieved, with reassessment if symptoms worsen 2

References

Guideline

Corneal Care Guidelines

Praxis Medical Insights: Practical Summaries of Clinical Guidelines, 2025

Guideline

Guideline Directed Topic Overview

Dr.Oracle Medical Advisory Board & Editors, 2025

Research

Corneal deposits following topical moxifloxacin use.

Saudi journal of ophthalmology : official journal of the Saudi Ophthalmological Society, 2019

Research

Antibiotic prophylaxis for corneal abrasion.

The Cochrane database of systematic reviews, 2022

Professional Medical Disclaimer

This information is intended for healthcare professionals. Any medical decision-making should rely on clinical judgment and independently verified information. The content provided herein does not replace professional discretion and should be considered supplementary to established clinical guidelines. Healthcare providers should verify all information against primary literature and current practice standards before application in patient care. Dr.Oracle assumes no liability for clinical decisions based on this content.

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