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Differential Diagnosis for Posterior Knee Pain

Single Most Likely Diagnosis

  • Baker's Cyst: A fluid-filled cyst that causes a bulge and a feeling of tightness behind the knee, often associated with knee arthritis or injury. This is the most common cause of posterior knee pain.

Other Likely Diagnoses

  • Hamstring Strain: A common injury that occurs when the hamstring muscles are stretched or torn, leading to pain and swelling in the posterior knee.
  • Gastrocnemius Strain: A strain of the calf muscle can cause pain in the posterior knee, especially when the knee is flexed.
  • Popliteus Tendinitis: Inflammation of the popliteus tendon, which connects the popliteus muscle to the lateral femur, can cause posterior knee pain.
  • Cystic Meniscal Tears: Tears in the meniscus can cause fluid-filled cysts to form, leading to posterior knee pain.

Do Not Miss Diagnoses

  • Deep Vein Thrombosis (DVT): A blood clot in the deep veins of the leg can cause posterior knee pain, swelling, and warmth. This is a medical emergency that requires prompt treatment.
  • Popliteal Artery Aneurysm: A bulge in the popliteal artery can cause posterior knee pain, swelling, and weakness in the leg.
  • Tumor: A tumor in the posterior knee, such as a sarcoma, can cause pain, swelling, and limited mobility.

Rare Diagnoses

  • Popliteal Cystic Adventitial Disease: A rare condition where a cyst forms in the adventitia of the popliteal artery, causing posterior knee pain and claudication.
  • Ganglion Cyst: A rare type of cyst that can form in the posterior knee, causing pain and limited mobility.
  • Osteochondroma: A rare type of bone tumor that can cause posterior knee pain and limited mobility.

Professional Medical Disclaimer

This information is intended for healthcare professionals. Any medical decision-making should rely on clinical judgment and independently verified information. The content provided herein does not replace professional discretion and should be considered supplementary to established clinical guidelines. Healthcare providers should verify all information against primary literature and current practice standards before application in patient care. Dr.Oracle assumes no liability for clinical decisions based on this content.

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