What is the starting dosage of Cialis (Tadalafil)?

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Last updated: February 10, 2025View editorial policy

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From the FDA Drug Label

The recommended starting dose of tadalafil tablets for use as needed in most patients is 10 mg, taken prior to anticipated sexual activity. The recommended starting dose of tadalafil tablets for once daily use is 2.5 mg, taken at approximately the same time every day, without regard to timing of sexual activity.

The starting dosage of Cialis (Tadalafil) is:

  • 10 mg for use as needed, taken prior to anticipated sexual activity
  • 2.5 mg for once daily use, taken at approximately the same time every day 1

From the Research

Starting Dosage of Cialis (Tadalafil)

The starting dosage of Cialis (Tadalafil) can vary depending on the specific treatment regimen and patient needs.

  • According to the study 2, the starting dosage of tadalafil was 5mg or 10mg taken once daily for the treatment of erectile dysfunction.
  • The study 3 also supports a starting dosage of 5mg once daily, with the option to adjust as needed.
  • Another study 4 mentions that the approved once-daily doses of tadalafil are 2.5mg or 5mg, with the 5mg dose being more effective.
  • The study 5 states that the starting dose of tadalafil was 10mg, which could be increased to 20mg or reduced to 5mg based on patient response and tolerability.
  • The study 6 reports that tadalafil was taken as needed at fixed 'on-demand' doses of 10 or 20 mg, with no specific starting dosage mentioned for daily use.

Key Findings

  • The efficacy and safety of tadalafil have been established in several studies, with starting dosages ranging from 2.5mg to 10mg once daily or as needed 2, 3, 4, 5, 6.
  • The most common adverse events associated with tadalafil include headache, dyspepsia, back pain, and myalgia 2, 3, 5, 6.

Professional Medical Disclaimer

This information is intended for healthcare professionals. Any medical decision-making should rely on clinical judgment and independently verified information. The content provided herein does not replace professional discretion and should be considered supplementary to established clinical guidelines. Healthcare providers should verify all information against primary literature and current practice standards before application in patient care. Dr.Oracle assumes no liability for clinical decisions based on this content.

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