Essential Dietary Supplements for Adults
The most essential dietary supplement for all adults is vitamin D (15 μg or 600 IU daily), as it is critical for bone health and is commonly deficient even in well-nourished populations. 1
Key Supplements Based on Evidence
High Priority Supplements
Vitamin D (15 μg/600 IU daily)
- Essential for bone health and prevention of frailty
- Natural food sources are limited, making supplementation necessary
- Deficiency is common, especially in winter months 1
Multivitamin-mineral supplement
Calcium (if dietary intake is insufficient)
Conditional Supplements (Based on Individual Factors)
Protein supplements
- Recommended for older adults or those with inadequate dietary protein
- Target: 1.1-1.5 g/kg ideal body weight daily
- High-quality protein with adequate leucine content is preferred 1
Iron
Zinc (15-30 mg daily)
- May be needed for those with malabsorption conditions
- Should maintain proper zinc-to-copper ratio (8-15:1) 3
Supplement Timing and Interactions
- Vitamin D: Can be taken any time of day
- Calcium: Best taken with dinner in divided doses (maximum 600 mg per dose) 3
- B vitamins: Best absorbed when taken with breakfast 3
- Zinc and calcium: Take at least 2 hours apart 3
- Iron and calcium: Take at least 2 hours apart 3
Important Considerations
Efficacy and Safety
- Beta-carotene supplements should be avoided, especially by smokers, due to increased lung cancer risk 1, 4
- Vitamin E supplements show no clear benefit for disease prevention 4
- Most supplements are well-tolerated when taken at recommended doses 2
Special Populations
- Older adults: Higher protein needs (1.1-1.5 g/kg), vitamin D (15 μg daily), and calcium requirements 1
- Women of reproductive age: Folic acid supplementation is recommended 5
- Post-bariatric surgery patients: Require comprehensive supplementation including higher doses of many nutrients 1
Common Pitfalls to Avoid
- Excessive supplementation: Taking more than recommended doses can lead to toxicity, especially with fat-soluble vitamins
- Relying solely on supplements: Dietary sources should remain the primary source of nutrients
- Ignoring interactions: Some supplements compete for absorption when taken together
- Self-prescribing without assessment: Blood tests should guide supplementation needs for many nutrients
Practical Implementation
- Start with a daily multivitamin-mineral supplement that includes adequate B vitamins
- Add vitamin D (15 μg/600 IU) if not included in sufficient amounts in the multivitamin
- Assess calcium intake from diet and supplement only if necessary
- Consider additional supplements based on individual risk factors, dietary patterns, or confirmed deficiencies
Remember that while supplements can help fill nutritional gaps, they should complement, not replace, a balanced diet rich in fruits, vegetables, whole grains, lean proteins, and healthy fats.