What is the pediatric dose for ibuprofen (Nonsteroidal Anti-Inflammatory Drug, NSAID)?

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Last updated: March 19, 2025View editorial policy

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From the Research

The recommended pediatric dose for ibuprofen is 5-10 mg per kilogram of body weight every 6-8 hours, not exceeding 40 mg/kg per day, as supported by the most recent and highest quality study 1.

Key Considerations

  • For children 6 months and older, the standard dosage is based on weight, with a maximum total daily dose of 30-40 mg/kg 1.
  • For infants under 6 months, it is crucial to consult a healthcare provider first before administering ibuprofen.
  • Liquid ibuprofen comes in different concentrations, so it's essential to check the product label and use the measuring device provided to ensure accurate dosing.

Administration and Safety

  • Ibuprofen should be given with food to minimize stomach upset.
  • Children should not take ibuprofen for more than 3 days for fever or 5 days for pain without consulting a healthcare provider.
  • If a child has kidney disease, heart problems, asthma, or is taking other medications, it is necessary to speak with a healthcare provider before administering ibuprofen.

Evidence Summary

The study by 1 provides the most recent and highest quality evidence for the pediatric dose of ibuprofen, emphasizing the importance of weight-based dosing and careful consideration of the child's overall health status. While other studies, such as 2, 3, 4, and 5, provide additional information on the efficacy and safety of ibuprofen in children, the study by 1 is the most relevant and reliable source for determining the recommended pediatric dose.

References

Research

A general overview of the use of ibuprofen in paediatrics.

International journal of clinical practice. Supplement, 2003

Research

Pharmacokinetics of ibuprofen in febrile children.

European journal of clinical pharmacology, 1991

Research

Ibuprofen suspension: pediatric antipyretic.

Pediatric nursing, 1996

Professional Medical Disclaimer

This information is intended for healthcare professionals. Any medical decision-making should rely on clinical judgment and independently verified information. The content provided herein does not replace professional discretion and should be considered supplementary to established clinical guidelines. Healthcare providers should verify all information against primary literature and current practice standards before application in patient care. Dr.Oracle assumes no liability for clinical decisions based on this content.

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