Dr. Urea 10% Cream Supply Information
Dr. Urea cream 10% is supplied as a topical cream formulation for dermatological use, primarily for treatment of dry skin conditions and hyperkeratosis. 1, 2
Formulation and Availability
- Dr. Urea 10% is available as a cream formulation 2
- It belongs to a family of urea-containing products that are available in various concentrations and formulations including:
- Creams
- Lotions
- Foams
- Ointments
- Gels 2
Clinical Applications
The 10% concentration of urea cream is specifically indicated for:
- Treatment of dry skin conditions 3
- Management of hyperkeratosis 1
- Prevention of palmar-plantar erythrodysesthesia syndrome (PPES) in patients receiving anticancer treatments 1
- Application to hands and feet for prevention of hand-foot skin reaction (HFSR) 1
Administration Guidelines
According to clinical guidelines, Dr. Urea 10% cream should be applied:
- Three times daily (t.i.d.) for prevention of PPES from capecitabine 1
- At least twice daily (b.i.d.) for prevention of PPES from doxorubicin and taxanes 1
- Applied to clean, dry skin and rubbed in gently until completely absorbed 4
- Best applied after bathing to improve skin hydration 4
Important Considerations
- Urea 10% cream is well tolerated but may cause burning sensation in some patients, particularly on inflamed skin 3, 5
- Should be avoided on:
- Face
- Flexural areas
- Areas with fissuring or broken skin 4
- The 10% concentration is appropriate for moderate dry skin conditions, while higher concentrations (>10%) are used for more severe hyperkeratosis 4, 6
Safety Profile
- Urea-based products at 10% concentration are generally well-tolerated 5
- Side effects are typically mild and more frequent at higher concentrations 6
- In clinical trials, the most common adverse effects were mild burning or itching sensation 5
Dr. Urea 10% cream is an effective moisturizer and keratolytic agent with established efficacy in multiple dermatological conditions, particularly those characterized by dry, scaly skin.