Differential Diagnosis for 1-year-old Male with CMV IgG Positive, Hypoglycemia, and Developmental Delays
- Single Most Likely Diagnosis
- Congenital CMV Infection: This is the most likely diagnosis given the patient's CMV IgG positive status, which indicates past or current infection. Congenital CMV infection can cause developmental delays, hearing loss, and vision impairment. Hypoglycemia can also occur due to CMV-induced pancreatitis or adrenal insufficiency.
- Other Likely Diagnoses
- Congenital Hypopituitarism: This condition can cause hypoglycemia due to deficiency of growth hormone or adrenocorticotropic hormone (ACTH). Developmental delays can also occur due to growth hormone deficiency.
- Pearson Syndrome: This rare mitochondrial disorder can cause hypoglycemia, developmental delays, and CMV infection due to immunodeficiency.
- Adrenal Insufficiency: This condition can cause hypoglycemia due to cortisol deficiency. Developmental delays can occur due to chronic illness or associated conditions like congenital adrenal hyperplasia.
- Do Not Miss Diagnoses
- Congenital Adrenal Hyperplasia (CAH): This condition can cause hypoglycemia due to cortisol deficiency and can be life-threatening if not treated promptly. Developmental delays can occur due to chronic illness or associated conditions.
- Hypoplastic Left Heart Syndrome: This congenital heart defect can cause hypoglycemia due to increased energy expenditure and can be life-threatening if not treated promptly. Developmental delays can occur due to chronic illness or associated conditions.
- Mitochondrial Disorders: These disorders can cause hypoglycemia, developmental delays, and CMV infection due to immunodeficiency. Some mitochondrial disorders can be life-threatening if not treated promptly.
- Rare Diagnoses
- Kabuki Syndrome: This rare genetic disorder can cause developmental delays, hypoglycemia, and increased susceptibility to infections like CMV.
- CHARGE Syndrome: This rare genetic disorder can cause developmental delays, hypoglycemia, and increased susceptibility to infections like CMV.
- Barth Syndrome: This rare X-linked genetic disorder can cause developmental delays, hypoglycemia, and increased susceptibility to infections like CMV due to immunodeficiency.