Initial Management Guidelines for CHF Patients Admitted to Hospital Floor
Patients with heart failure admitted with evidence of significant fluid overload should be promptly treated with intravenous loop diuretics to reduce morbidity and mortality. 1
Initial Assessment
Volume status evaluation:
- Assess for pulmonary/systemic congestion
- Check orthostatic blood pressure changes
- Measure weight and calculate BMI
- Monitor daily weights throughout hospitalization
Laboratory workup:
- Complete blood count
- Serum electrolytes (including calcium and magnesium)
- BUN and creatinine
- Liver function tests
- Cardiac biomarkers (troponin, BNP/NT-proBNP)
- Thyroid function tests
Diagnostic studies:
- 12-lead ECG to evaluate for ischemia or arrhythmias
- Chest radiograph (PA and lateral) to confirm pulmonary edema
- Echocardiography to assess LVEF, wall motion, and valve function
Immediate Management
Diuretic Therapy
- IV loop diuretics are first-line treatment for volume overload 1
- Initial IV dose should equal or exceed chronic oral daily dose
- Can be given as intermittent boluses or continuous infusion
- Monitor urine output, symptoms, and signs of congestion
- Adjust dose to relieve symptoms and reduce volume excess while avoiding hypotension
When Diuresis is Inadequate
- Consider higher doses of IV loop diuretics 1
- Add a second diuretic (e.g., thiazide) 1
- Low-dose dopamine infusion may be considered to improve diuresis and preserve renal function 1
- Ultrafiltration may be considered for patients with obvious volume overload not responding to diuretics 1
Vasodilator Therapy
- For severely symptomatic fluid overload without hypotension, consider adding:
- IV nitroglycerin
- IV nitroprusside
- IV nesiritide
- Especially beneficial when added to diuretics or when diuretics alone are insufficient 1
Medication Management
Continuation of Chronic Medications
- Continue guideline-directed medical therapy (GDMT) in patients with HFrEF unless hemodynamically unstable or contraindicated 1
- This includes:
- ACE inhibitors/ARBs
- Beta-blockers
- Aldosterone antagonists
Beta-Blocker Therapy
- Continue beta-blockers in most patients with HF, especially those with concomitant hypertension 1
- Consider withholding or reducing beta-blockers only in:
- Patients with recent initiation or increase in beta-blocker therapy
- Marked volume overload
- Patients requiring inotropes during hospitalization 1
- Initiate beta-blockers at low dose only after:
- Optimization of volume status
- Successful discontinuation of IV diuretics, vasodilators, and inotropic agents
- Patient is hemodynamically stable 1
ACE Inhibitors/ARBs
- Consider reducing or temporarily discontinuing in patients with:
- Worsening azotemia
- Until renal function improves 1
Monitoring During Hospitalization
Daily assessment of:
Consider invasive hemodynamic monitoring for selected patients with:
- Persistent symptoms despite empiric therapy adjustment
- Uncertain fluid status or vascular resistance
- Low systolic BP with symptoms despite initial therapy
- Worsening renal function with therapy
- Need for parenteral vasoactive agents 1
Transition of Care
Transition from IV to oral diuretics with careful attention to:
- Oral diuretic dosing
- Monitoring of electrolytes
- Monitor for hypotension and worsening renal function 1
Discharge planning:
- Provide comprehensive written discharge instructions covering:
- Diet (sodium and fluid restrictions)
- Discharge medications
- Activity level
- Follow-up appointments
- Daily weight monitoring
- Instructions for worsening symptoms 1
- Provide comprehensive written discharge instructions covering:
Common Pitfalls to Avoid
Inadequate diuresis: Many patients are discharged after minimal weight loss. Ensure adequate volume status before discharge.
Premature discontinuation of chronic medications: Continue GDMT unless specifically contraindicated.
Failure to identify precipitating factors: Always investigate potential causes of decompensation:
- Medication non-adherence
- Dietary indiscretion (sodium/fluid)
- Acute coronary syndrome
- Arrhythmias
- Infections
- Uncontrolled hypertension
Overlooking comorbidities: Address concurrent conditions that may exacerbate HF:
- Coronary artery disease
- Hypertension
- Valvular heart disease
- Arrhythmias
- Renal dysfunction
- Diabetes
- Thromboembolic disease
Inadequate thromboembolism prophylaxis: This is recommended for all hospitalized HF patients 1
By following these guidelines, clinicians can optimize outcomes for patients hospitalized with CHF, reducing morbidity, mortality, and the risk of readmission.