Treatment of Bell's Palsy
Oral corticosteroids are strongly recommended as first-line treatment for Bell's palsy, with prednisolone 50-60mg daily for 5 days followed by a 5-day taper showing significantly improved recovery rates. 1, 2
First-Line Treatment
- Corticosteroid therapy:
- Prednisolone 50-60mg daily for 5 days followed by a 5-day taper 1, 2
- Should be started as early as possible, ideally within 72 hours of symptom onset 3
- High-quality evidence shows significantly improved recovery rates with early steroid administration 1
- Studies demonstrate that prednisolone shortens time to complete recovery (HR 1.40,95% CI 1.18-1.64) 4
- Recovery rates increase from approximately 70% with no treatment to 83-94% with prednisolone 3
Antiviral Therapy
- Antiviral agents (optional):
- May be considered in combination with corticosteroids 1
- Options include valacyclovir (1g three times daily for 7 days) or acyclovir (400mg five times daily for 10 days) 2
- Evidence for antiviral therapy alone is insufficient, and it is not recommended as monotherapy 1, 2, 3
- Some studies suggest combination therapy may reduce rates of synkinesis (involuntary co-contraction of facial muscles) 2
- The most recent high-quality evidence shows minimal additional benefit when combined with steroids (RR 0.75,95% CI 0.56-1.00) 1
Critical Eye Protection
- Eye protection is crucial for patients with impaired eye closure:
- Artificial tears during daytime
- Lubricating ointment at night
- Taping eyelids closed if necessary to prevent corneal damage 1
- Failure to protect the eye can lead to corneal ulceration, a serious complication
Additional Management
- Physical therapy may be beneficial for patients with more severe paralysis 2
- Supportive care for patients with dysphagia
- Referral to facial nerve specialist if swallowing difficulties persist beyond 3 months 1
Special Populations
Elderly patients (>60 years):
- May particularly benefit from combination therapy with corticosteroids and antivirals
- One study showed 100% recovery in elderly patients treated with valacyclovir and prednisone versus only 42% in untreated controls 5
Children and pregnant women:
- Have higher spontaneous recovery rates (up to 90%) even without treatment 2
- Treatment decisions should still follow standard guidelines but with consideration of risk-benefit ratio
Common Pitfalls
- Delayed treatment - Corticosteroids should be initiated within 72 hours of symptom onset for maximum benefit
- Neglecting eye protection - Can lead to serious corneal complications
- Using antivirals alone - Not effective as monotherapy
- Misdiagnosis - Ensure proper diagnosis of Bell's palsy by excluding other causes of facial weakness
- Unnecessary imaging - Neuroimaging should not be performed routinely but reserved for specific indications 1