What is the diagnosis for a patient with a benign-appearing axillary lymph node, normal bone mineralization, and no evidence of fracture, dislocation, or soft tissue mass?

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Differential Diagnosis

  • Single most likely diagnosis
    • Benign lymph node: The presence of a benign-appearing axillary lymph node with a thin uniform cortex and prominent fatty hilum, as described in the findings, is most consistent with a benign lymph node. The lack of lymphadenopathy or other suspicious features supports this diagnosis.
  • Other Likely diagnoses
    • Reactive lymphadenopathy: Although the lymph node is described as benign, it is still possible that it represents a reactive process, which could be caused by a variety of factors such as infection or inflammation.
    • Lipoma or other benign soft tissue mass: Although no discrete soft tissue mass was identified, it is possible that a small lipoma or other benign mass could be present and not visualized on the current imaging.
  • Do Not Miss (ddxs that may not be likely, but would be deadly if missed.)
    • Lymphoma: Although the lymph node appears benign, lymphoma is a potentially life-threatening condition that must be considered, especially if symptoms persist.
    • Metastatic disease: The presence of an axillary lymph node, even if benign-appearing, raises the possibility of metastatic disease, particularly if there is a known primary malignancy.
    • Infection or abscess: Although there is no significant inflammatory stranding or induration, an infectious process or abscess could still be present and would require prompt treatment.
  • Rare diagnoses
    • Castleman disease: A rare condition characterized by lymph node hyperplasia, which could potentially present with a benign-appearing lymph node.
    • Kimura disease: A rare condition characterized by lymphadenopathy and eosinophilia, which could potentially present with a benign-appearing lymph node.
    • Other rare lymphoproliferative disorders: There are several rare lymphoproliferative disorders that could potentially present with a benign-appearing lymph node, such as Rosai-Dorfman disease or Langerhans cell histiocytosis.

Professional Medical Disclaimer

This information is intended for healthcare professionals. Any medical decision-making should rely on clinical judgment and independently verified information. The content provided herein does not replace professional discretion and should be considered supplementary to established clinical guidelines. Healthcare providers should verify all information against primary literature and current practice standards before application in patient care. Dr.Oracle assumes no liability for clinical decisions based on this content.

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