What are the differential diagnoses for vomiting at 30 weeks (weeks of gestation) of pregnancy?

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Last updated: March 19, 2025View editorial policy

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Differential Diagnosis for Vomiting at 30 Weeks Gestation

  • Single Most Likely Diagnosis
    • Hyperemesis gravidarum: This condition is a common cause of vomiting in pregnancy, especially during the first and second trimesters, but can persist. It is characterized by excessive vomiting, leading to dehydration and weight loss.
  • Other Likely Diagnoses
    • Gastroenteritis: Viral or bacterial infections can cause vomiting in pregnant women, similar to the non-pregnant population.
    • Urinary tract infection (UTI): UTIs are common in pregnancy due to physiological changes and can cause symptoms such as nausea and vomiting.
    • Preeclampsia: Although more commonly associated with hypertension and proteinuria, some women with preeclampsia may experience nausea and vomiting.
  • Do Not Miss Diagnoses
    • Appendicitis: Although rare in pregnancy, appendicitis can present with nausea and vomiting. Delayed diagnosis can lead to severe consequences for both the mother and the fetus.
    • Placental abruption: This condition involves the placenta separating from the uterus and can cause severe abdominal pain, vomiting, and vaginal bleeding.
    • HELLP syndrome: A variant of preeclampsia, characterized by hemolysis, elevated liver enzymes, and low platelet count, which can present with nausea and vomiting among other symptoms.
  • Rare Diagnoses
    • Hydatidiform mole: A rare condition where a non-viable fertilized egg implants in the uterus, leading to severe nausea and vomiting.
    • Intrahepatic cholestasis of pregnancy (ICP): A condition causing severe itching and can lead to nausea and vomiting due to bile duct obstruction.
    • Pancreatitis: Inflammation of the pancreas, which can cause severe abdominal pain, nausea, and vomiting, and is rare in pregnancy.

Professional Medical Disclaimer

This information is intended for healthcare professionals. Any medical decision-making should rely on clinical judgment and independently verified information. The content provided herein does not replace professional discretion and should be considered supplementary to established clinical guidelines. Healthcare providers should verify all information against primary literature and current practice standards before application in patient care. Dr.Oracle assumes no liability for clinical decisions based on this content.

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