Discharge Instructions for Strep Throat
Patients diagnosed with strep throat should complete a full 10-day course of antibiotics, even if symptoms improve, to prevent acute rheumatic fever and ensure complete bacterial eradication. 1
Medication Instructions
Antibiotic Treatment
- Penicillin-based antibiotics are the first-line treatment:
- Take antibiotics at the start of a meal to minimize gastrointestinal intolerance 2
- For penicillin-allergic patients:
- Clindamycin 300-450 mg orally three times daily for 10 days (adults)
- Azithromycin 12 mg/kg once daily (maximum 500 mg) for 5 days (children) 1
Pain Relief
- Ibuprofen: 400 mg every 6-8 hours (adults); 5-10 mg/kg every 6-8 hours (children)
- Acetaminophen (Paracetamol): 500-1000 mg every 4-6 hours (adults); 10-15 mg/kg every 4-6 hours (children)
- Do not give aspirin to children due to risk of Reye syndrome 1
Infection Control Measures
- Stay home from school/work for at least 24 hours after starting antibiotics 1, 3
- You remain contagious until you've been on antibiotics for 24 hours
- Wash hands frequently with soap and water
- Do not share utensils, drinks, or personal items
- Cover mouth when coughing or sneezing
- Dispose of used tissues properly 1
Home Care Instructions
- Complete the entire antibiotic course (full 10 days) even if you feel better 1, 2, 4
- Stay hydrated by drinking plenty of fluids
- Use throat lozenges or warm salt water gargles for sore throat relief
- Get plenty of rest to support recovery
- Replace toothbrush after 24-48 hours of antibiotic treatment to prevent reinfection
When to Seek Medical Attention
Return to the healthcare provider if:
- Symptoms do not improve within 48-72 hours of starting antibiotics
- Fever persists beyond 48 hours of treatment
- Difficulty swallowing or breathing develops
- Rash appears after starting antibiotics
- Symptoms worsen or new symptoms develop
Follow-up Instructions
- No routine follow-up is needed if symptoms resolve
- If you experience recurrent strep throat (≥7 episodes in the past year, ≥5 episodes per year for 2 years, or ≥3 episodes per year for 3 years), follow up with your provider to discuss possible tonsillectomy 1
Important Notes
- Shortened antibiotic courses (5-7 days) are being studied but are not currently recommended by guidelines 5, 6
- The standard 10-day course is crucial to prevent complications like acute rheumatic fever 1, 2, 4
- Most patients become culture-negative within 24 hours of starting antibiotics, but a full 24-hour period is recommended before returning to school/work 3