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Last updated: September 28, 2025View editorial policy

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Differential Diagnosis for Uncircumcised Redness to Penile Head

  • Single Most Likely Diagnosis
    • Balanitis: This is an inflammation of the glans penis and is common in uncircumcised males due to the warm, moist environment under the foreskin, which can lead to bacterial or fungal infections. Poor hygiene can exacerbate this condition.
  • Other Likely Diagnoses
    • Contact Dermatitis: An allergic reaction or irritation from soaps, detergents, or other substances can cause redness and inflammation on the penile head.
    • Phimosis: A condition where the foreskin cannot be fully retracted over the glans, which can lead to irritation, redness, and potential infection due to trapped moisture and debris.
    • Urinary Tract Infection (UTI): While less common in men, UTIs can cause irritation and redness of the genital area, including the penile head.
  • Do Not Miss Diagnoses
    • Cancer (e.g., Squamous Cell Carcinoma): Although rare, penile cancer can present with redness, lesions, or ulcers on the penile head. Early detection is crucial for effective treatment.
    • Sexually Transmitted Infections (STIs): Conditions like syphilis, gonorrhea, or herpes can cause redness, sores, or lesions on the genital area, including the penile head. Prompt diagnosis and treatment are essential to prevent complications and transmission.
  • Rare Diagnoses
    • Lichen Sclerosus: A chronic inflammatory skin condition that can affect the genital area, leading to thinning of the skin, redness, and potential scarring.
    • Psoriasis: An autoimmune condition that can cause red, scaly patches on various parts of the body, including the genital area.
    • Erythroplasia of Queyrat: A rare condition characterized by red, velvety lesions on the mucous membranes, including the genital area, which can be precancerous.

Professional Medical Disclaimer

This information is intended for healthcare professionals. Any medical decision-making should rely on clinical judgment and independently verified information. The content provided herein does not replace professional discretion and should be considered supplementary to established clinical guidelines. Healthcare providers should verify all information against primary literature and current practice standards before application in patient care. Dr.Oracle assumes no liability for clinical decisions based on this content.

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